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NCT00525837 · ClinicalTrials.gov registry record · NA
Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers
A NA study, sponsored by Butler Hospital.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
NCT00525837: Completed NA study, sponsored by Butler Hospital.
NCT00525837 is a NA study that has completed, run by Butler Hospital. The registered enrollment target is 18 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00525837, a NA study, has completed, sponsored by Butler Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
Study Summary
This study will assess whether varenicline (chantix) has antidepressant properties when used in addition to other psychiatric medication. It will also assess whether varenicline improves the inability to feel pleasure (i.e. anhedonia), and if it is well-tolerated when used with psychiatric medications. Enrolled patients will be assessed for improved mood, improved anhedonia, overall sense of health, side effects as well as tobacco use for 6-8 weeks. Medication will be provided free of charge.
Primary Outcome
this is a 16-item self report questionnaire that measures depressive symptoms. Improvement is reported in change in depressive score score ranges from 0-27, with higher numbers indicating more severe symptom reporting. change is calculated by baseline plus/minus the value at the later time point
Interventions
- DRUG varenicline
- DRUG fixed dose varenicline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2007-09 |
| Est. Completion | 2008-03 |
| Phase | NA |
What the finished NCT00525837 record still lists
NCT00525837 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which varenicline is the first listed.
NCT00525837 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00525837 about?
NCT00525837 is a clinical study titled "Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers". This study will assess whether varenicline (chantix) has antidepressant properties when used in addition to other psychiatric medication. It will also assess whether varenicline improves the inability to feel pleasure (i.e. anhedonia), and if it is well-tolerated when used with psychiatric medicatio...
What is the current status of trial NCT00525837?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2007-09. Estimated completion is 2008-03.
What interventions are being tested in trial NCT00525837?
The interventions under investigation include: varenicline (DRUG), fixed dose varenicline (DRUG).
Who is sponsoring clinical trial NCT00525837?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00525837's enrollment target sits among peer trials
18 1863rd of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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