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NCT00523640 · ClinicalTrials.gov registry record · Phase 2

A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma

A Phase 2 study, sponsored by University of Chicago.

Terminated
Registry status
Phase 2
Development phase
30
Enrollment target

NCT00523640: Clinical Trial Phase 2 study, sponsored by University of Chicago.

NCT00523640 is a Phase 2 study that was terminated before completion, run by University of Chicago. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00523640, a Phase 2 study, was terminated before completion, sponsored by University of Chicago.

TERMINATED
Registry status
Phase 2
Development phase
30 participants
Enrollment target

Study Summary

The purpose of this study is to find out what effects (good and bad) the combination of the chemotherapy drugs gemcitabine, capecitabine, and bevacizumab has on a patient and kidney cancer.

Primary Outcome

Per RECIST Criteria (V1.0) using standard cross-sectional CT scanning: Complete Response (CR), Disappearance of all target lesions; Partial Response (PR), \>=30% decrease in the sum of the longest diameter of target lesions; Response (R)= CR + PR.

Interventions

  • DRUG combination of gemcitabine, capecitabine, and bevacizumab

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2005-03
Est. Completion 2011-04
Phase Phase 2
University of Chicago

796 total trials

Why NCT00523640 stopped before completion

NCT00523640 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which combination of gemcitabine, capecitabine, and bevacizumab is the first listed.

NCT00523640 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00523640 about?

NCT00523640 is a clinical study titled "A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma". The purpose of this study is to find out what effects (good and bad) the combination of the chemotherapy drugs gemcitabine, capecitabine, and bevacizumab has on a patient and kidney cancer.

What is the current status of trial NCT00523640?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2005-03. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00523640?

The interventions under investigation include: combination of gemcitabine, capecitabine, and bevacizumab (DRUG).

Who is sponsoring clinical trial NCT00523640?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00523640's enrollment target sits among peer trials

30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00523640, the US trial registry maintained by the National Library of Medicine. NCT00523640 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.