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NCT00508443 · ClinicalTrials.gov registry record · Phase 1
Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)
A Phase 1 study of Spinal Neoplasms, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 1
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT00508443: Active Phase 1 study of Spinal Neoplasms, sponsored by M.D. Anderson Cancer Center.
NCT00508443 is a Phase 1 study of Spinal Neoplasms that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 150 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (150% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00508443, a Phase 1 study of Spinal Neoplasms, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical research study is to find out if stereotactic spine radiotherapy is safe and effective in the treatment of metastatic spine tumors. The feasibility of this type of treatment will be studied as will any side effects related to the treatment. The precision and accuracy of the CT-on-rails will also be studied.
Primary Outcome
The validated Brief Pain Inventory (BPI), MD Anderson Symptom Inventory (MDASI), and SF-12v2 Health Survey used to assess changes in these indicators compared to pre-treatment baseline. Response determined by follow-up questionaires. Time to maximal pain relief is the time from the first day of irradiation until the lowest pain score for average pain after radiotherapy. The "worst pain score" from BPI used as the marker for treatment success or failure.
Conditions Studied
Interventions
- RADIATION Radiation Therapy
Study Locations (1)
Texas
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2002-10-25 |
| Est. Completion | 2026-10-31 |
| Phase | Phase 1 |
What the registry record for NCT00508443 still lists
NCT00508443 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (150% higher).
The record links to 1 condition, with Spinal Neoplasms appearing as the primary indexed condition, and to 1 intervention - of which Radiation Therapy is the first listed.
NCT00508443 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00508443 about?
NCT00508443 is a clinical study titled "Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)". The goal of this clinical research study is to find out if stereotactic spine radiotherapy is safe and effective in the treatment of metastatic spine tumors. The feasibility of this type of treatment will be studied as will any side effects related to the treatment. The precision and accuracy of the...
What is the current status of trial NCT00508443?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2002-10-25. Estimated completion is 2026-10-31.
What conditions does trial NCT00508443 study?
This clinical trial studies the following conditions: Spinal Neoplasms.
What interventions are being tested in trial NCT00508443?
The interventions under investigation include: Radiation Therapy (RADIATION).
Who is sponsoring clinical trial NCT00508443?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00508443 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00508443's enrollment target sits among peer trials
150 363rd of 2000 higher than 1,620 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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