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NCT00502216 · ClinicalTrials.gov registry record · Phase 1
Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT00502216: Completed Phase 1 study, sponsored by Yale University.
NCT00502216 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00502216, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether the combination of naltrexone (Depade) and varenicline (Chantix) minimizes post-smoking cessation weight gain and how well the combination is tolerated.
Interventions
- DRUG Varenicline
- DRUG Naltrexone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2007-07 |
| Est. Completion | 2009-06 |
| Phase | Phase 1 |
What the finished NCT00502216 record still lists
NCT00502216 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which Varenicline is the first listed.
NCT00502216 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00502216 about?
NCT00502216 is a clinical study titled "Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers". The purpose of this study is to determine whether the combination of naltrexone (Depade) and varenicline (Chantix) minimizes post-smoking cessation weight gain and how well the combination is tolerated.
What is the current status of trial NCT00502216?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2007-07. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00502216?
The interventions under investigation include: Varenicline (DRUG), Naltrexone (DRUG).
Who is sponsoring clinical trial NCT00502216?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00502216's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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