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NCT00499707 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects
A Phase 3 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 3
- Development phase
- 453
- Enrollment target
NCT00499707: Completed Phase 3 study, sponsored by GlaxoSmithKline.
NCT00499707 is a Phase 3 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 453 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00499707, a Phase 3 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 453 participants
- Enrollment target
Study Summary
The purpose of this 32 week study is to demonstrate that fixed-dose combination treatment with rosiglitazone/metformin will safely and effectively control glycemia as first line oral therapy in subjects type 2 diabetes. The primary objective of the study is to demonstrate superiority of rosiglitazone/metformin compared to its rosiglitazone and metformin.
Interventions
- DRUG rosiglitazone maleate/metformin hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 453 participants |
| Start Date | 2003-10-08 |
| Est. Completion | 2004-12-16 |
| Phase | Phase 3 |
What the finished NCT00499707 record still lists
NCT00499707 is an interventional study that assigns participants to a tested intervention. The registered 453 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (41% lower).
The record links to 0 conditions, and to 1 intervention - of which rosiglitazone maleate/metformin hydrochloride is the first listed.
NCT00499707 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00499707 about?
NCT00499707 is a clinical study titled "Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects". The purpose of this 32 week study is to demonstrate that fixed-dose combination treatment with rosiglitazone/metformin will safely and effectively control glycemia as first line oral therapy in subjects type 2 diabetes. The primary objective of the study is to demonstrate superiority of rosiglitazon...
What is the current status of trial NCT00499707?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 453 participants. The study started on 2003-10-08. Estimated completion is 2004-12-16.
What interventions are being tested in trial NCT00499707?
The interventions under investigation include: rosiglitazone maleate/metformin hydrochloride (DRUG).
Who is sponsoring clinical trial NCT00499707?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00499707's enrollment target sits among peer trials
453 834th of 2000 higher than 1,166 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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