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NCT00498654 · ClinicalTrials.gov registry record · Phase 2

Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects

A Phase 2 study, sponsored by Avant Immunotherapeutics.

Completed
Registry status
Phase 2
Development phase
180
Enrollment target

NCT00498654: Completed Phase 2 study, sponsored by Avant Immunotherapeutics.

NCT00498654 is a Phase 2 study that has completed, run by Avant Immunotherapeutics. The registered enrollment target is 180 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00498654, a Phase 2 study, has completed, sponsored by Avant Immunotherapeutics.

COMPLETED
Registry status
Phase 2
Development phase
180 participants
Enrollment target

Study Summary

The purpose of this trial is to examine the safety and immunogenicity of Ty800 oral vaccine in healthy adult subjects.

Interventions

  • BIOLOGICAL Ty800 (Salmonella typhi) Oral Vaccine

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2007-07
Est. Completion 2008-06
Phase Phase 2
Avant Immunotherapeutics

2 total trials

What the finished NCT00498654 record still lists

NCT00498654 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (35% higher).

The record links to 0 conditions, and to 1 intervention - of which Ty800 (Salmonella typhi) Oral Vaccine is the first listed.

NCT00498654 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00498654 about?

NCT00498654 is a clinical study titled "Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects". The purpose of this trial is to examine the safety and immunogenicity of Ty800 oral vaccine in healthy adult subjects.

What is the current status of trial NCT00498654?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2007-07. Estimated completion is 2008-06.

What interventions are being tested in trial NCT00498654?

The interventions under investigation include: Ty800 (Salmonella typhi) Oral Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00498654?

This trial is sponsored by Avant Immunotherapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00498654's enrollment target sits among peer trials

180 365th of 2000 higher than 1,610 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00498654, the US trial registry maintained by the National Library of Medicine. NCT00498654 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.