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NCT00494546 · ClinicalTrials.gov registry record · Phase 3
High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer
A Phase 3 study, sponsored by VA Puget Sound Health Care System.
- Completed
- Registry status
- Phase 3
- Development phase
- 568
- Enrollment target
NCT00494546: Completed Phase 3 study, sponsored by VA Puget Sound Health Care System.
NCT00494546 is a Phase 3 study that has completed, run by VA Puget Sound Health Care System. The registered enrollment target is 568 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (26% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00494546, a Phase 3 study, has completed, sponsored by VA Puget Sound Health Care System.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 568 participants
- Enrollment target
Study Summary
Objective: The objective of this study is test the hypothesis that delivering a higher percentage of the radiation dose as external radiation versus implant will lead to higher tumor control rates. Research design A total of 600 patients with AJC clinical stage T1-T2 prostatic carcinoma (Gleason grade 7 to 10 and/or PSA 10 to 20 ng/ml) will be randomized to treatment with 44 Gy versus 20 Gy external radiation plus a Pd-103 implant boost (90 Gy versus 105 Gy, respectively).
Interventions
- PROCEDURE Pd-103 with 20 vs 44 Gy supplemental beam XRT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 568 participants |
| Start Date | 1999-01 |
| Est. Completion | 2007-06 |
| Phase | Phase 3 |
What the finished NCT00494546 record still lists
NCT00494546 is an interventional study that assigns participants to a tested intervention. The registered 568 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (26% lower).
The record links to 0 conditions, and to 1 intervention - of which Pd-103 with 20 vs 44 Gy supplemental beam XRT is the first listed.
NCT00494546 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00494546 about?
NCT00494546 is a clinical study titled "High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer". Objective: The objective of this study is test the hypothesis that delivering a higher percentage of the radiation dose as external radiation versus implant will lead to higher tumor control rates. Research design A total of 600 patients with AJC clinical stage T1-T2 prostatic carcinoma (Gleason gr...
What is the current status of trial NCT00494546?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 568 participants. The study started on 1999-01. Estimated completion is 2007-06.
What interventions are being tested in trial NCT00494546?
The interventions under investigation include: Pd-103 with 20 vs 44 Gy supplemental beam XRT (PROCEDURE).
Who is sponsoring clinical trial NCT00494546?
This trial is sponsored by VA Puget Sound Health Care System, which has 16 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00494546's enrollment target sits among peer trials
568 666th of 2000 higher than 1,334 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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