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NCT00488267 · ClinicalTrials.gov registry record · Phase 3
Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee
A Phase 3 study of Osteoarthritis, sponsored by ZARS Pharma.
- Completed
- Registry status
- Phase 3
- Development phase
- 679
- Enrollment target
- 20
- Study locations
NCT00488267: Completed Phase 3 study of Osteoarthritis, sponsored by ZARS Pharma.
NCT00488267 is a Phase 3 study of Osteoarthritis that has completed, run by ZARS Pharma. The registered enrollment target is 679 participants, below the 813-participant average among 135 other Osteoarthritis trials with a reported enrollment target (16% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00488267, a Phase 3 study of Osteoarthritis, has completed, sponsored by ZARS Pharma.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 679 participants
- Enrollment target
- 20
- Study locations
Study Summary
ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis. This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with osteoarthritis of the knee in adults.
Conditions Studied
Interventions
- DRUG ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System)
- DRUG Placebo Matrix/CHADD Patch
- DRUG Ketoprofen matrix/placebo CHADD Patch
Study Locations (20)
Florida
- - Clearwater
- - Jupiter
- - Pembroke Pines
- - South Miami
- - Tampa
California
- - Anaheim
- - Buena Park
- - San Diego
- - Westlake Village
Connecticut
- - Hamden
- - Milford
Maryland
- - Baltimore
- - Wheaton
Arizona
- - Peoria
Idaho
- - Boise
Illinois
- - Springfield
Indiana
- - Evansville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 679 participants |
| Start Date | 2007-06 |
| Est. Completion | 2008-09 |
| Phase | Phase 3 |
What the finished NCT00488267 record still lists
NCT00488267 is an interventional study that assigns participants to a tested intervention. The registered 679 participants enrollment target is mid-sized for trials with a published cap, below the 813-participant average among 135 other Osteoarthritis trials with a reported enrollment target (16% lower).
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 3 interventions - of which ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System) is the first listed.
NCT00488267 names 20 study sites across 11 states, led by Florida, California, Connecticut.
Frequently Asked Questions
What is clinical trial NCT00488267 about?
NCT00488267 is a clinical study titled "Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee". ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis. This study will evaluate ThermoProfen for the treatment of mild to moderate pain associated with...
What is the current status of trial NCT00488267?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 679 participants. The study started on 2007-06. Estimated completion is 2008-09.
What conditions does trial NCT00488267 study?
This clinical trial studies the following conditions: Osteoarthritis.
What interventions are being tested in trial NCT00488267?
The interventions under investigation include: ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System) (DRUG), Placebo Matrix/CHADD Patch (DRUG), Ketoprofen matrix/placebo CHADD Patch (DRUG).
Who is sponsoring clinical trial NCT00488267?
This trial is sponsored by ZARS Pharma, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00488267 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00488267's enrollment target sits among peer trials
679 20th of 135 higher than 116 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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