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NCT00477490 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety of Desmopressin Melt for the Treatment of Nocturia
A Phase 3 study of Nocturia, sponsored by Ferring Pharmaceuticals.
- Completed
- Registry status
- Phase 3
- Development phase
- 799
- Enrollment target
- 20
- Study locations
NCT00477490: Completed Phase 3 study of Nocturia, sponsored by Ferring Pharmaceuticals.
NCT00477490 is a Phase 3 study of Nocturia that has completed, run by Ferring Pharmaceuticals. The registered enrollment target is 799 participants, above the 228-participant average among 9 other Nocturia trials with a reported enrollment target (250% higher). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00477490, a Phase 3 study of Nocturia, has completed, sponsored by Ferring Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 799 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to investigate the efficacy and safety of several doses of the melt formulation of desmopressin in a broad population of adult patients with nocturia.
Primary Outcome
The number of nocturnal voids was the average over 3 consecutive 24-hours periods prior to Day 1 and prior to the week 4 visit as recorded in participant diaries. This was the first co-primary outcome.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG desmopressin acetate
Study Locations (20)
California
- Advanced Urology Medical Center - Anaheim
- Impact Clinical Trials - Beverly Hills
- Atlantic Urology Medical Group - Long Beach
- California Professional Research - Newport Beach
- San Diego Uro-Research - San Diego
- Radiant Research - Santa Rosa
- West Coast Clinical Research - Tarzana
- Western Clinical Research - Torrance
Florida
- South Florida Medical Research - Aventura
- Women's Medical Research Group, LLC - Clearwater
- Medsearch Professional Group - Miami
- Sunrise Medical Research - Plantation
- Radiant Research - Stuart
Colorado
- Urology Associates PC - Denver
- Downtown Women's Health Care - Denver
- Genitourinary Surgical Consultants - Denver
Alabama
- Radiant Research - Birmingham
Arizona
- Radiant Research - Scottsdale
Arkansas
- Arkansas Primary Care Clinic - Little Rock
Connecticut
- Connecticut Clinical Research Center, LLC - Middlebury
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 799 participants |
| Start Date | 2007-05 |
| Est. Completion | 2008-02 |
| Phase | Phase 3 |
What the finished NCT00477490 record still lists
NCT00477490 is an interventional study that assigns participants to a tested intervention. The registered 799 participants enrollment target is mid-sized for trials with a published cap, above the 228-participant average among 9 other Nocturia trials with a reported enrollment target (250% higher).
The record links to 1 condition, with Nocturia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00477490 names 20 study sites across 7 states, led by California, Florida, Colorado.
Frequently Asked Questions
What is clinical trial NCT00477490 about?
NCT00477490 is a clinical study titled "Efficacy and Safety of Desmopressin Melt for the Treatment of Nocturia". The purpose of this study is to investigate the efficacy and safety of several doses of the melt formulation of desmopressin in a broad population of adult patients with nocturia.
What is the current status of trial NCT00477490?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 799 participants. The study started on 2007-05. Estimated completion is 2008-02.
What conditions does trial NCT00477490 study?
This clinical trial studies the following conditions: Nocturia.
What interventions are being tested in trial NCT00477490?
The interventions under investigation include: Placebo (DRUG), desmopressin acetate (DRUG).
Who is sponsoring clinical trial NCT00477490?
This trial is sponsored by Ferring Pharmaceuticals, which has 83 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00477490 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Nocturia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00477490's enrollment target sits among peer trials
799 1st of 9 higher than 9 of 9 other Nocturia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Nocturia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Study Investigating the Impact Burden of Nocturia Using the Nocturia Impact Diary
COMPLETED · Phase 3
-
An Extension Study Investigating the Efficacy and Safety of a Fast-Dissolving ("Melt") Formulation of Desmopressin for the Treatment of Nocturia in Adults
COMPLETED · Phase 3
-
Long Term Safety Assessment of SER120 in Patients With Nocturia
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Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
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-
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
RECRUITING · NA
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