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NCT00473577 · ClinicalTrials.gov registry record · Phase 1
Study of the Tolerability, Safety, and Pharmacokinetics of CRA-024781 in Cancer Patients
A Phase 1 study, sponsored by Pharmacyclics.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT00473577: Completed Phase 1 study, sponsored by Pharmacyclics.
NCT00473577 is a Phase 1 study that has completed, run by Pharmacyclics. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00473577, a Phase 1 study, has completed, sponsored by Pharmacyclics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
To determine the maximum tolerated dose (MTD) of CRA-024781 IV given by 2-hour intravenous infusions in patients with refractory solid or hematologic malignancies. To evaluate safety and tolerability, pharmacokinetics and pharmacodynamics, and to evaluate bioavailability of CRA-024781 IV when administered in a single oral dose.
Interventions
- DRUG CRA-24781
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2005-08 |
| Est. Completion | 2007-12 |
| Phase | Phase 1 |
What the finished NCT00473577 record still lists
NCT00473577 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 1 intervention - of which CRA-24781 is the first listed.
NCT00473577 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00473577 about?
NCT00473577 is a clinical study titled "Study of the Tolerability, Safety, and Pharmacokinetics of CRA-024781 in Cancer Patients". To determine the maximum tolerated dose (MTD) of CRA-024781 IV given by 2-hour intravenous infusions in patients with refractory solid or hematologic malignancies. To evaluate safety and tolerability, pharmacokinetics and pharmacodynamics, and to evaluate bioavailability of CRA-024781 IV when admini...
What is the current status of trial NCT00473577?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2005-08. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00473577?
The interventions under investigation include: CRA-24781 (DRUG).
Who is sponsoring clinical trial NCT00473577?
This trial is sponsored by Pharmacyclics, which has 54 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00473577's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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