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NCT00469911 · ClinicalTrials.gov registry record · NA
Quantification of Intramyocardial Lipid by Proton Magnetic Resonance Spectroscopy
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
NCT00469911: Completed NA study, sponsored by Washington University School of Medicine.
NCT00469911 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 18 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00469911, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
Study Summary
Accumulation of triglycerides in heart tissue has been associated with changes in left ventricular function which can lead to heart failure. Proton magnetic resonance spectroscopy is currently the only non-invasive in vivo method to measure myocardial triglycerides content. The primary goal of this study was to determine if Magnetic Resonance Spectroscopy could effectively measure myocardial triglyceride content in myocardial heart tissue. Thus, quantitative and reliable techniques to monitor in vivo triglyceride accumulation in the heart are important for disease diagnosis and management. Currently, no such imaging method exists.
Primary Outcome
Participants first had MRS spectroscopy then the MRS spectroscopy images were compared to endomyocardial biopsy
Interventions
- PROCEDURE Magnetic Resonance Spectroscopy
- PROCEDURE Ex vivo heart biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2005-08 |
| Est. Completion | 2009-06 |
| Phase | NA |
What the finished NCT00469911 record still lists
NCT00469911 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Magnetic Resonance Spectroscopy is the first listed.
NCT00469911 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00469911 about?
NCT00469911 is a clinical study titled "Quantification of Intramyocardial Lipid by Proton Magnetic Resonance Spectroscopy". Accumulation of triglycerides in heart tissue has been associated with changes in left ventricular function which can lead to heart failure. Proton magnetic resonance spectroscopy is currently the only non-invasive in vivo method to measure myocardial triglycerides content. The primary goal of this ...
What is the current status of trial NCT00469911?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2005-08. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00469911?
The interventions under investigation include: Magnetic Resonance Spectroscopy (PROCEDURE), Ex vivo heart biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT00469911?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00469911's enrollment target sits among peer trials
18 1863rd of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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