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NCT00469833 · ClinicalTrials.gov registry record · NA
Insulin Secretion in Diabetes Before and After Glycemic Control
A NA study of Diabetes and Hyperglycemia, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- NA
- Development phase
- 17
- Enrollment target
- 1
- Study location
NCT00469833: Completed NA study of Diabetes and Hyperglycemia, sponsored by US Department of Veterans Affairs.
NCT00469833 is a NA study of Diabetes and Hyperglycemia that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 17 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00469833, a NA study of Diabetes and Hyperglycemia, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- NA
- Development phase
- 17 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this project is to understand defects in insulin secretion that contribute to abnormal glucose metabolism in patients with diabetes. In particular the effects of signals released from the intestine to stimulate insulin secretion will be tested. Patients with type 2 diabetes will have insulin secretion in response to glucose and intestinal factors before and after insulin treatment to lower their blood glucose. It is expected that the results of this work will provide valuable information for treating diabetic people.
Primary Outcome
Subjects had glucose clamps for 270 minutes with serial sampling of blood for measurement of insulin and C-peptide. At 90 minutes into the clamp they consumed 75 g of oral glucose solution. Meal-stimulated insulin secretion was summarized as the mean plasma C-peptide from 90-270 minutes. This outcome measure was compared for each subject before treatment and after 2 months of insulin treatment to lower blood glucose. Subjects were started on 20 units of insulin glargine after their first visit a
Conditions Studied
Interventions
- DRUG insulin glargine
Study Locations (1)
Ohio
- VA Medical Center, Cincinnati - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2008-04 |
| Est. Completion | 2012-09 |
| Phase | NA |
What the finished NCT00469833 record still lists
NCT00469833 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 1 intervention - of which insulin glargine is the first listed.
NCT00469833 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT00469833 about?
NCT00469833 is a clinical study titled "Insulin Secretion in Diabetes Before and After Glycemic Control". The objective of this project is to understand defects in insulin secretion that contribute to abnormal glucose metabolism in patients with diabetes. In particular the effects of signals released from the intestine to stimulate insulin secretion will be tested. Patients with type 2 diabetes will hav...
What is the current status of trial NCT00469833?
This trial is currently completed. It is a NA study. The enrollment target is 17 participants. The study started on 2008-04. Estimated completion is 2012-09.
What conditions does trial NCT00469833 study?
This clinical trial studies the following conditions: Diabetes, Hyperglycemia.
What interventions are being tested in trial NCT00469833?
The interventions under investigation include: insulin glargine (DRUG).
Who is sponsoring clinical trial NCT00469833?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00469833 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00469833's enrollment target sits among peer trials
17 317th of 338 higher than 21 of 338 other Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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