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NCT00464347 · ClinicalTrials.gov registry record · Phase 2
TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration
A Phase 2 study, sponsored by National Eye Institute (NEI).
- Terminated
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00464347: Clinical Trial Phase 2 study, sponsored by National Eye Institute (NEI).
NCT00464347 is a Phase 2 study that was terminated before completion, run by National Eye Institute (NEI). The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00464347, a Phase 2 study, was terminated before completion, sponsored by National Eye Institute (NEI).
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
VERTACL will investigate whether a triple therapy, Avastin®, half fluence verteporfin photodynamic therapy (PDT), and triamcinolone acetonide-preservative free (TAC- PF), results in improved 12-month vision outcome compared to Avastin® alone in participants with neovascular AMD.
Interventions
- DRUG Avastin
- PROCEDURE Photodynamic Therapy (PDT)
- DRUG Preservative-Free Triamcinolone Acetonide (TAC-PF)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2007-01 |
| Est. Completion | 2007-09 |
| Phase | Phase 2 |
Why NCT00464347 stopped before completion
NCT00464347 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 3 interventions - of which Avastin is the first listed.
NCT00464347 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00464347 about?
NCT00464347 is a clinical study titled "TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration". VERTACL will investigate whether a triple therapy, Avastin®, half fluence verteporfin photodynamic therapy (PDT), and triamcinolone acetonide-preservative free (TAC- PF), results in improved 12-month vision outcome compared to Avastin® alone in participants with neovascular AMD.
What is the current status of trial NCT00464347?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2007-01. Estimated completion is 2007-09.
What interventions are being tested in trial NCT00464347?
The interventions under investigation include: Avastin (DRUG), Photodynamic Therapy (PDT) (PROCEDURE), Preservative-Free Triamcinolone Acetonide (TAC-PF) (DRUG).
Who is sponsoring clinical trial NCT00464347?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00464347's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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