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NCT00462488 · ClinicalTrials.gov registry record · Phase 2
Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ
A Phase 2 study, sponsored by Sesen Bio.
- Completed
- Registry status
- Phase 2
- Development phase
- 46
- Enrollment target
NCT00462488: Completed Phase 2 study, sponsored by Sesen Bio.
NCT00462488 is a Phase 2 study that has completed, run by Sesen Bio. The registered enrollment target is 46 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00462488, a Phase 2 study, has completed, sponsored by Sesen Bio.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 46 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy and tolerability of Vicinium when administered as a monotherapy intravesical instillation in patients with non-invasive urothelial carcinoma in situ (CIS) who failed previous treatment with Bacille Calmette Guérin (BCG).
Primary Outcome
Complete response rate in subjects with carcinoma in situ (CIS) non-muscle invasive bladder cancer (NMIBC) following the induction phase (3-month evaluation point) of Vicinium treatment
Interventions
- DRUG Vicinium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2007-03 |
| Est. Completion | 2009-10 |
| Phase | Phase 2 |
What the finished NCT00462488 record still lists
NCT00462488 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower).
The record links to 0 conditions, and to 1 intervention - of which Vicinium is the first listed.
NCT00462488 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00462488 about?
NCT00462488 is a clinical study titled "Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ". The purpose of this study is to evaluate the efficacy and tolerability of Vicinium when administered as a monotherapy intravesical instillation in patients with non-invasive urothelial carcinoma in situ (CIS) who failed previous treatment with Bacille Calmette Guérin (BCG).
What is the current status of trial NCT00462488?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2007-03. Estimated completion is 2009-10.
What interventions are being tested in trial NCT00462488?
The interventions under investigation include: Vicinium (DRUG).
Who is sponsoring clinical trial NCT00462488?
This trial is sponsored by Sesen Bio, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00462488's enrollment target sits among peer trials
46 1286th of 2000 higher than 705 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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