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NCT00460642 · ClinicalTrials.gov registry record · NA
GnRH Antagonist to Prepare Recipients for Embryo Transfer
A NA study of Infertility, sponsored by Institute for Human Reproduction (IHR).
- Completed
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 2
- Study locations
NCT00460642: Completed NA study of Infertility, sponsored by Institute for Human Reproduction (IHR).
NCT00460642 is a NA study of Infertility that has completed, run by Institute for Human Reproduction (IHR). The registered enrollment target is 130 participants, below the 7,588-participant average among 74 other Infertility trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00460642, a NA study of Infertility, has completed, sponsored by Institute for Human Reproduction (IHR).
- COMPLETED
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 2
- Study locations
Study Summary
26% of all ART cycles performed in the USA in 2003 (CDC data) are frozen embryo transfers (FET) and transfer of embryos resulting from egg donation (ED) to recipients. The typical protocol used to prepare a recipient for ET involves GnRH agonist (Lupron, Tap Pharmaceuticals) to down regulate the patient. A GnRH antagonist, such as Cetrotide (EMD Serono), is comparable to GnRH agonist and FDA approved to prevent spontaneous ovulation with ART treatment, and its usage decreases significantly the number of injections that the patient receives with treatment. The working hypothesis for this study is that the GnRH antagonist (Cetrotide) can be used instead of an agonist to achieve effective down regulation in FET and ED cycles. Presumably, patients will prefer Cetrotide over Lupron because of the markedly fewer injections required.
Conditions Studied
Interventions
- DRUG GnRH Antagonist (Cetrotide)
Study Locations (2)
Illinois
- Institute for Human Reproduction (IHR) - Chicago
- Institute for Human Reproduction (IHR) - Oakbrook Terrace
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2007-01 |
| Est. Completion | 2009-12 |
| Phase | NA |
What the finished NCT00460642 record still lists
NCT00460642 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 7,588-participant average among 74 other Infertility trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Infertility appearing as the primary indexed condition, and to 1 intervention - of which GnRH Antagonist (Cetrotide) is the first listed.
NCT00460642 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00460642 about?
NCT00460642 is a clinical study titled "GnRH Antagonist to Prepare Recipients for Embryo Transfer". 26% of all ART cycles performed in the USA in 2003 (CDC data) are frozen embryo transfers (FET) and transfer of embryos resulting from egg donation (ED) to recipients. The typical protocol used to prepare a recipient for ET involves GnRH agonist (Lupron, Tap Pharmaceuticals) to down regulate the pat...
What is the current status of trial NCT00460642?
This trial is currently completed. It is a NA study. The enrollment target is 130 participants. The study started on 2007-01. Estimated completion is 2009-12.
What conditions does trial NCT00460642 study?
This clinical trial studies the following conditions: Infertility.
What interventions are being tested in trial NCT00460642?
The interventions under investigation include: GnRH Antagonist (Cetrotide) (DRUG).
Who is sponsoring clinical trial NCT00460642?
This trial is sponsored by Institute for Human Reproduction (IHR), which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00460642 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00460642's enrollment target sits among peer trials
130 51st of 74 higher than 24 of 74 other Infertility trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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