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NCT00460642 · ClinicalTrials.gov registry record · NA

GnRH Antagonist to Prepare Recipients for Embryo Transfer

A NA study of Infertility, sponsored by Institute for Human Reproduction (IHR).

Completed
Registry status
NA
Development phase
130
Enrollment target
2
Study locations

NCT00460642 is a NA study of Infertility that has completed, run by Institute for Human Reproduction (IHR). The registered enrollment target is 130 participants, below the 7,588-participant average among 74 other Infertility trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT00460642, a NA study of Infertility, has completed, sponsored by Institute for Human Reproduction (IHR).

COMPLETED
Registry status
NA
Development phase
130 participants
Enrollment target
2
Study locations

Study Summary

26% of all ART cycles performed in the USA in 2003 (CDC data) are frozen embryo transfers (FET) and transfer of embryos resulting from egg donation (ED) to recipients. The typical protocol used to prepare a recipient for ET involves GnRH agonist (Lupron, Tap Pharmaceuticals) to down regulate the patient. A GnRH antagonist, such as Cetrotide (EMD Serono), is comparable to GnRH agonist and FDA approved to prevent spontaneous ovulation with ART treatment, and its usage decreases significantly the number of injections that the patient receives with treatment. The working hypothesis for this study is that the GnRH antagonist (Cetrotide) can be used instead of an agonist to achieve effective down regulation in FET and ED cycles. Presumably, patients will prefer Cetrotide over Lupron because of the markedly fewer injections required.

Conditions Studied

Interventions

  • DRUG GnRH Antagonist (Cetrotide)

Study Locations (2)

Illinois

  • Institute for Human Reproduction (IHR) - Chicago
  • Institute for Human Reproduction (IHR) - Oakbrook Terrace

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2007-01
Est. Completion 2009-12
Phase NA

What the Registry Record Tells You About NCT00460642

The ClinicalTrials.gov registry entry for NCT00460642 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,588-participant average among 74 other Infertility trials with a reported enrollment target (98% lower). The listed sponsor is Institute for Human Reproduction (IHR), which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Infertility appearing as the primary indexed condition, and to 1 intervention - of which GnRH Antagonist (Cetrotide) is the first listed.

NCT00460642 reports 2 study locations spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00460642 about?

NCT00460642 is a clinical study titled "GnRH Antagonist to Prepare Recipients for Embryo Transfer". 26% of all ART cycles performed in the USA in 2003 (CDC data) are frozen embryo transfers (FET) and transfer of embryos resulting from egg donation (ED) to recipients. The typical protocol used to prepare a recipient for ET involves GnRH agonist (Lupron, Tap Pharmaceuticals) to down regulate the pat...

What is the current status of trial NCT00460642?

This trial is currently completed. It is a NA study. The enrollment target is 130 participants. The study started on 2007-01. Estimated completion is 2009-12.

What conditions does trial NCT00460642 study?

This clinical trial studies the following conditions: Infertility.

What interventions are being tested in trial NCT00460642?

The interventions under investigation include: GnRH Antagonist (Cetrotide) (DRUG).

Who is sponsoring clinical trial NCT00460642?

This trial is sponsored by Institute for Human Reproduction (IHR), which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00460642 being conducted?

This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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