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NCT00459056 · ClinicalTrials.gov registry record · Phase 3
The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive Patients
A Phase 3 study, sponsored by St. Paul Heart Clinic.
- Completed
- Registry status
- Phase 3
- Development phase
- 25
- Enrollment target
NCT00459056: Completed Phase 3 study, sponsored by St. Paul Heart Clinic.
NCT00459056 is a Phase 3 study that has completed, run by St. Paul Heart Clinic. The registered enrollment target is 25 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00459056, a Phase 3 study, has completed, sponsored by St. Paul Heart Clinic.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the effects of two different combination therapies for high blood pressure on vascular health.
Primary Outcome
Reactive hyperemic index is a measure of endothelial function. This is measured by the ratio of post-occlusion blood volume flow versus the baseline blood volume flow. The outcome reported is the change in this ratio after the first intervention phase compared to after the second intervention phase.
Interventions
- DRUG Carvedilol CR + Lisinopril
- DRUG Lisinopril + HCTZ
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2007-04 |
| Est. Completion | 2010-05 |
| Phase | Phase 3 |
What the finished NCT00459056 record still lists
NCT00459056 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Carvedilol CR + Lisinopril is the first listed.
NCT00459056 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00459056 about?
NCT00459056 is a clinical study titled "The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive Patients". The purpose of this study is to compare the effects of two different combination therapies for high blood pressure on vascular health.
What is the current status of trial NCT00459056?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 25 participants. The study started on 2007-04. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00459056?
The interventions under investigation include: Carvedilol CR + Lisinopril (DRUG), Lisinopril + HCTZ (DRUG).
Who is sponsoring clinical trial NCT00459056?
This trial is sponsored by St. Paul Heart Clinic, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00459056's enrollment target sits among peer trials
25 1941st of 2000 higher than 58 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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