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NCT00457665 · ClinicalTrials.gov registry record · Phase 4
Mechanisms of Lipodystrophy in HIV-Infected Pateints
A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 56
- Enrollment target
NCT00457665: Completed Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
NCT00457665 is a Phase 4 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 56 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00457665, a Phase 4 study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 56 participants
- Enrollment target
Study Summary
The metabolic and molecular basis of lipodystrophy syndrome in HIV-infected patients is not known. Whether besides protease inhibitors, other antiretroviral drugs, HIV infection and reduction in viral load contribute to the development of lipodystrophy syndrome is not clear. The project therefore has the following aims: 1) to characterize metabolic abnormalities and changes in body fat distribution, 2) to develop objective criteria for defining the syndrome and to ascertain prognostic indicators and 3) to elucidate the molecular basis of the lipodystrophy syndrome in HIV-infected patients.
Interventions
- DRUG Nelfinavir
- DRUG Efavirenz
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2002-02 |
| Est. Completion | 2014-10 |
| Phase | Phase 4 |
What the finished NCT00457665 record still lists
NCT00457665 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which Nelfinavir is the first listed.
NCT00457665 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00457665 about?
NCT00457665 is a clinical study titled "Mechanisms of Lipodystrophy in HIV-Infected Pateints". The metabolic and molecular basis of lipodystrophy syndrome in HIV-infected patients is not known. Whether besides protease inhibitors, other antiretroviral drugs, HIV infection and reduction in viral load contribute to the development of lipodystrophy syndrome is not clear. The project therefore h...
What is the current status of trial NCT00457665?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 56 participants. The study started on 2002-02. Estimated completion is 2014-10.
What interventions are being tested in trial NCT00457665?
The interventions under investigation include: Nelfinavir (DRUG), Efavirenz (DRUG).
Who is sponsoring clinical trial NCT00457665?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00457665's enrollment target sits among peer trials
56 1213th of 2000 higher than 783 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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