Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00454220 · ClinicalTrials.gov registry record · Phase 2

Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter

A Phase 2 study, sponsored by Genzyme, a Sanofi Company.

Completed
Registry status
Phase 2
Development phase
96
Enrollment target

NCT00454220 is a Phase 2 study that has completed, run by Genzyme, a Sanofi Company. The registered enrollment target is 96 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00454220, a Phase 2 study, has completed, sponsored by Genzyme, a Sanofi Company.

COMPLETED
Registry status
Phase 2
Development phase
96 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and effectiveness of 2 different doses of modified-release recombinant human thyroid stimulating hormone (MRrhTSH) when administered with radioiodine in patients with multinodular goiter, a condition that involves the enlargement of the thyroid gland. We will also evaluate the safety and effectiveness of radioiodine therapy alone in these patients. The goal of the treatment is to determine if there was a reduction in the size of the goiter and to study if goiter symptoms have improved after 6 months and after 36 months.

Interventions

  • OTHER Placebo
  • DRUG MRrhTSH

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2007-07
Est. Completion 2011-07
Phase Phase 2

Sponsor

Genzyme, a Sanofi Company

196 total trials

What the Registry Record Tells You About NCT00454220

The ClinicalTrials.gov registry entry for NCT00454220 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genzyme, a Sanofi Company, which has 196 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00454220 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00454220 about?

NCT00454220 is a clinical study titled "Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter". The purpose of this study is to determine the safety and effectiveness of 2 different doses of modified-release recombinant human thyroid stimulating hormone (MRrhTSH) when administered with radioiodine in patients with multinodular goiter, a condition that involves the enlargement of the thyroid gl...

What is the current status of trial NCT00454220?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 96 participants. The study started on 2007-07. Estimated completion is 2011-07.

What interventions are being tested in trial NCT00454220?

The interventions under investigation include: Placebo (OTHER), MRrhTSH (DRUG).

Who is sponsoring clinical trial NCT00454220?

This trial is sponsored by Genzyme, a Sanofi Company, which has 196 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.