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NCT00452114 · ClinicalTrials.gov registry record · NA
In-exsufflator Cough Assist Device in Patients With Symptomatic Bronchiectasis
A NA study, sponsored by University of Massachusetts, Worcester.
- Terminated
- Registry status
- NA
- Development phase
- 28
- Enrollment target
NCT00452114: Clinical Trial NA study, sponsored by University of Massachusetts, Worcester.
NCT00452114 is a NA study that was terminated before completion, run by University of Massachusetts, Worcester. The registered enrollment target is 28 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00452114, a NA study, was terminated before completion, sponsored by University of Massachusetts, Worcester.
- TERMINATED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
Study Summary
This study is a randomized, controlled trial examining the effectiveness of the mechanical cough-assist device (in-exsufflator) in promoting the clearance of retained airway secretions in patients with symptomatic bronchiectasis. We hypothesize that this enhanced clearance of airway secretions will lead to a decline in the number of acute exacerbations of bronchiectasis experienced by these patients during the study period, improve health-related quality of life, decrease overall health-care costs and improve pulmonary function.
Primary Outcome
The impact of the intervention is measured by the total number of suppurative exacerbations per patient within a 12 month period.
Interventions
- DEVICE In-Exsufflator Cough Assist Device
- DEVICE Active Comparator: Flutter Valve Device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2004-04 |
| Est. Completion | 2008-05 |
| Phase | NA |
Why NCT00452114 stopped before completion
NCT00452114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which In-Exsufflator Cough Assist Device is the first listed.
NCT00452114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00452114 about?
NCT00452114 is a clinical study titled "In-exsufflator Cough Assist Device in Patients With Symptomatic Bronchiectasis". This study is a randomized, controlled trial examining the effectiveness of the mechanical cough-assist device (in-exsufflator) in promoting the clearance of retained airway secretions in patients with symptomatic bronchiectasis. We hypothesize that this enhanced clearance of airway secretions will ...
What is the current status of trial NCT00452114?
This trial is currently terminated. It is a NA study. The enrollment target is 28 participants. The study started on 2004-04. Estimated completion is 2008-05.
What interventions are being tested in trial NCT00452114?
The interventions under investigation include: In-Exsufflator Cough Assist Device (DEVICE), Active Comparator: Flutter Valve Device (DEVICE).
Who is sponsoring clinical trial NCT00452114?
This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00452114's enrollment target sits among peer trials
28 1704th of 2000 higher than 293 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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