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NCT00448643 · ClinicalTrials.gov registry record · Phase 1
Whole-Abdominal Radiation Therapy and Cisplatin in Treating Patients With Stage III or Stage IV Endometrial Cancer That Has Been Removed by Surgery
A Phase 1 study, sponsored by University of Miami.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT00448643: Completed Phase 1 study, sponsored by University of Miami.
NCT00448643 is a Phase 1 study that has completed, run by University of Miami. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00448643, a Phase 1 study, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Radiation therapy may also make tumor cells more sensitive to cisplatin. Giving radiation therapy together with cisplatin after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase I trial is studying the side effects and best dose of whole-abdominal radiation therapy when given together with cisplatin in treating patients with stage III or stage IV endometrial cancer that has been removed by surgery.
Interventions
- DRUG Cisplatin
- RADIATION Vaginal Brachytherapy
- RADIATION Whole Abdominal Radiation [WAR] Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2002-05 |
| Est. Completion | 2011-03 |
| Phase | Phase 1 |
What the finished NCT00448643 record still lists
NCT00448643 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 3 interventions - of which Cisplatin is the first listed.
NCT00448643 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00448643 about?
NCT00448643 is a clinical study titled "Whole-Abdominal Radiation Therapy and Cisplatin in Treating Patients With Stage III or Stage IV Endometrial Cancer That Has Been Removed by Surgery". RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Radiation therapy may also make tumor cells more sensitive...
What is the current status of trial NCT00448643?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2002-05. Estimated completion is 2011-03.
What interventions are being tested in trial NCT00448643?
The interventions under investigation include: Cisplatin (DRUG), Vaginal Brachytherapy (RADIATION), Whole Abdominal Radiation [WAR] Therapy (RADIATION).
Who is sponsoring clinical trial NCT00448643?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00448643's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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