Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00448227 · ClinicalTrials.gov registry record · Phase 2

Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection

A Phase 2 study, sponsored by Novartis.

Completed
Registry status
Phase 2
Development phase
18
Enrollment target

NCT00448227: Completed Phase 2 study, sponsored by Novartis.

NCT00448227 is a Phase 2 study that has completed, run by Novartis. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00448227, a Phase 2 study, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 2
Development phase
18 participants
Enrollment target

Study Summary

This study will evaluate the acceptability and safety of famciclovir in infants with herpes simplex infection

Primary Outcome

Measured by Tmax - The time after administration of a drug when the maximum plasma concentration is reached.

Interventions

  • DRUG famciclovir

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2007-10
Phase Phase 2
Novartis

265 total trials

What the finished NCT00448227 record still lists

NCT00448227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 1 intervention - of which famciclovir is the first listed.

NCT00448227 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00448227 about?

NCT00448227 is a clinical study titled "Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection". This study will evaluate the acceptability and safety of famciclovir in infants with herpes simplex infection

What is the current status of trial NCT00448227?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2007-10.

What interventions are being tested in trial NCT00448227?

The interventions under investigation include: famciclovir (DRUG).

Who is sponsoring clinical trial NCT00448227?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00448227's enrollment target sits among peer trials

18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01245179 · 18 participants · Phase 1

    Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

  • NCT01999361 · 18 participants · NA

    Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss

  • NCT02359825 · 18 participants · Phase 1

    Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function

  • NCT02870244 · 18 participants · Phase 1

    Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00448227, the US trial registry maintained by the National Library of Medicine. NCT00448227 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.