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NCT00445458 · ClinicalTrials.gov registry record · Phase 1
A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer
A Phase 1 study, sponsored by Puma Biotechnology.
- Completed
- Registry status
- Phase 1
- Development phase
- 110
- Enrollment target
NCT00445458 is a Phase 1 study that has completed, run by Puma Biotechnology. The registered enrollment target is 110 participants.
The verdict
NCT00445458, a Phase 1 study, has completed, sponsored by Puma Biotechnology.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 110 participants
- Enrollment target
Study Summary
The purpose of this study is to learn whether it is safe and effective to administer HKI-272 (neratinib) in combination with paclitaxel in patients with breast cancer.
Interventions
- DRUG Paclitaxel
- DRUG HKI-272
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2007-09-11 |
| Est. Completion | 2018-02-07 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00445458
The ClinicalTrials.gov registry entry for NCT00445458 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Puma Biotechnology, which has 28 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Paclitaxel is the first listed.
NCT00445458 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00445458 about?
NCT00445458 is a clinical study titled "A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer". The purpose of this study is to learn whether it is safe and effective to administer HKI-272 (neratinib) in combination with paclitaxel in patients with breast cancer.
What is the current status of trial NCT00445458?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 110 participants. The study started on 2007-09-11. Estimated completion is 2018-02-07.
What interventions are being tested in trial NCT00445458?
The interventions under investigation include: Paclitaxel (DRUG), HKI-272 (DRUG).
Who is sponsoring clinical trial NCT00445458?
This trial is sponsored by Puma Biotechnology, which has 28 total clinical trials registered on ClinicalTrials.gov.
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