Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00439244 · ClinicalTrials.gov registry record · Phase 3

Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis

A Phase 3 study, sponsored by Novartis.

Completed
Registry status
Phase 3
Development phase
412
Enrollment target

NCT00439244: Completed Phase 3 study, sponsored by Novartis.

NCT00439244 is a Phase 3 study that has completed, run by Novartis. The registered enrollment target is 412 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00439244, a Phase 3 study, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 3
Development phase
412 participants
Enrollment target

Study Summary

The purpose of this study is to assess the effects of zoledronic acid administered at the same time with teriparatide compared to zoledronic acid alone and teriparatide alone on bone mineral density (BMD) gain in the lumbar spine and total hip

Primary Outcome

BMD measurements of the lumbar spine (L1-L4) by Dual X-ray absorptiometry (DXA) were performed on all patients at screening, and Weeks 13, 26, and 52 (or early termination). Every attempt was made to obtain the BMD measurements at the scheduled visit. If this was not possible, a BMD measurement ± 7 days from the scheduled visit was obtained. For the Final DXA at Week 52, the window was 10 - 15 days prior to the final study visit. BMD scans were acquired locally and all results sent to a central

Interventions

  • DRUG Placebo
  • DRUG Zoledronic acid
  • DRUG Teriparatide

Trial Details

FieldValue
Enrollment Target 412 participants
Start Date 2006-12
Est. Completion 2009-02
Phase Phase 3
Novartis

265 total trials

What the finished NCT00439244 record still lists

NCT00439244 is an interventional study that assigns participants to a tested intervention. The registered 412 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00439244 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00439244 about?

NCT00439244 is a clinical study titled "Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis". The purpose of this study is to assess the effects of zoledronic acid administered at the same time with teriparatide compared to zoledronic acid alone and teriparatide alone on bone mineral density (BMD) gain in the lumbar spine and total hip

What is the current status of trial NCT00439244?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 412 participants. The study started on 2006-12. Estimated completion is 2009-02.

What interventions are being tested in trial NCT00439244?

The interventions under investigation include: Placebo (DRUG), Zoledronic acid (DRUG), Teriparatide (DRUG).

Who is sponsoring clinical trial NCT00439244?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00439244's enrollment target sits among peer trials

412 906th of 2000 higher than 1,092 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05993689 · 412 participants · NA

    Building TrUst and UNiting Teams Through DouLa partnErship - BUNDLE

  • NCT06699212 · 412 participants · Phase 3

    A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

  • NCT03592472 · 413 participants · Phase 3

    A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

  • NCT06697197 · 413 participants · Phase 1

    A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00439244, the US trial registry maintained by the National Library of Medicine. NCT00439244 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.