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NCT00436852 · ClinicalTrials.gov registry record · Phase 2

ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment

A Phase 2 study, sponsored by Children's Oncology Group.

Completed
Registry status
Phase 2
Development phase
92
Enrollment target

NCT00436852: Completed Phase 2 study, sponsored by Children's Oncology Group.

NCT00436852 is a Phase 2 study that has completed, run by Children's Oncology Group. The registered enrollment target is 92 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00436852, a Phase 2 study, has completed, sponsored by Children's Oncology Group.

COMPLETED
Registry status
Phase 2
Development phase
92 participants
Enrollment target

Study Summary

This phase II trial is studying how well ABT-751 works in treating children with neuroblastoma that has relapsed or not responded to previous treatment. Drugs used in chemotherapy, such as ABT-751, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.

Primary Outcome

Median time to progression observed on ABT-751, along with 95% confidence intervals.

Interventions

  • PROCEDURE quality-of-life assessment
  • DRUG ABT-751

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2007-01
Est. Completion 2015-03-30
Phase Phase 2
Children's Oncology Group

342 total trials

What the finished NCT00436852 record still lists

NCT00436852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower).

The record links to 0 conditions, and to 2 interventions - of which quality-of-life assessment is the first listed.

NCT00436852 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00436852 about?

NCT00436852 is a clinical study titled "ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment". This phase II trial is studying how well ABT-751 works in treating children with neuroblastoma that has relapsed or not responded to previous treatment. Drugs used in chemotherapy, such as ABT-751, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping t...

What is the current status of trial NCT00436852?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2007-01. Estimated completion is 2015-03-30.

What interventions are being tested in trial NCT00436852?

The interventions under investigation include: quality-of-life assessment (PROCEDURE), ABT-751 (DRUG).

Who is sponsoring clinical trial NCT00436852?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00436852's enrollment target sits among peer trials

92 767th of 2000 higher than 1,230 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00436852, the US trial registry maintained by the National Library of Medicine. NCT00436852 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.