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NCT00436332 · ClinicalTrials.gov registry record · Phase 2

S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
84
Enrollment target

NCT00436332: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT00436332 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 84 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00436332, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
84 participants
Enrollment target

Study Summary

RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving erlotinib together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving erlotinib together with bevacizumab works in treating patients with stage III or stage IV non-small cell lung cancer.

Interventions

  • BIOLOGICAL bevacizumab
  • DRUG erlotinib hydrochloride

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2007-07
Est. Completion 2019-08-20
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT00436332 record still lists

NCT00436332 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower).

The record links to 0 conditions, and to 2 interventions - of which bevacizumab is the first listed.

NCT00436332 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00436332 about?

NCT00436332 is a clinical study titled "S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma". RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them o...

What is the current status of trial NCT00436332?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2007-07. Estimated completion is 2019-08-20.

What interventions are being tested in trial NCT00436332?

The interventions under investigation include: bevacizumab (BIOLOGICAL), erlotinib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00436332?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00436332's enrollment target sits among peer trials

84 822nd of 2000 higher than 1,173 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00436332, the US trial registry maintained by the National Library of Medicine. NCT00436332 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.