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NCT00435994 · ClinicalTrials.gov registry record · NA
Assessment of Airway Obstruction in Infants With Lower Respiratory Infections
A NA study, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 59
- Enrollment target
NCT00435994: Completed NA study, sponsored by Indiana University.
NCT00435994 is a NA study that has completed, run by Indiana University. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00435994, a NA study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 59 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate how two different aerosol medications may improve airway function in infants with respiratory illness. We are using two different medications and comparing the difference in lung function after each medication. We will also be taking a nasal wash sample for VEGF. We will be using this in comparing how infants respond to the aerosol medications as well. We hope to help standardize medications used for infants with bronchiolitis and RSV.
Primary Outcome
Lung functions were obtained under sedation using Chloral Hydrate. Forced expiratory flows are a lung volume at which the airway pressure is equal to 30 cm H2O (V30). Forced expiratory flows are measured at 75% FVC (FEF75). Measurements were repeated post bronchodilator and again post Epinephrine. A higher Z-score reflects better lung function.
Interventions
- DRUG Inhaled primatene will be given as a breathing treatment
- OTHER Nasal Washing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2003-12 |
| Est. Completion | 2012-12 |
| Phase | NA |
What the finished NCT00435994 record still lists
NCT00435994 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Inhaled primatene will be given as a breathing treatment is the first listed.
NCT00435994 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00435994 about?
NCT00435994 is a clinical study titled "Assessment of Airway Obstruction in Infants With Lower Respiratory Infections". The purpose of this study is to evaluate how two different aerosol medications may improve airway function in infants with respiratory illness. We are using two different medications and comparing the difference in lung function after each medication. We will also be taking a nasal wash sample for V...
What is the current status of trial NCT00435994?
This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2003-12. Estimated completion is 2012-12.
What interventions are being tested in trial NCT00435994?
The interventions under investigation include: Inhaled primatene will be given as a breathing treatment (DRUG), Nasal Washing (OTHER).
Who is sponsoring clinical trial NCT00435994?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00435994's enrollment target sits among peer trials
59 1256th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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