Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00427154 · ClinicalTrials.gov registry record · Phase 3
Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes
A Phase 3 study, sponsored by Novo Nordisk A/S.
- Terminated
- Registry status
- Phase 3
- Development phase
- 227
- Enrollment target
NCT00427154: Clinical Trial Phase 3 study, sponsored by Novo Nordisk A/S.
NCT00427154 is a Phase 3 study that was terminated before completion, run by Novo Nordisk A/S. The registered enrollment target is 227 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00427154, a Phase 3 study, was terminated before completion, sponsored by Novo Nordisk A/S.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 227 participants
- Enrollment target
Study Summary
This trial is conducted in the United States of America (USA). This trial will compare the changes in HbA1c after 26 weeks of inhaled insulin or rosiglitazone treatment, both in combination with metformin and glimepiride.
Interventions
- DRUG metformin
- DRUG rosiglitazone
- DRUG glimepiride
- DRUG inhaled human insulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 227 participants |
| Start Date | 2007-01-10 |
| Est. Completion | 2008-03-11 |
| Phase | Phase 3 |
Why NCT00427154 stopped before completion
NCT00427154 is an interventional study that assigns participants to a tested intervention. The registered 227 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 4 interventions - of which metformin is the first listed.
NCT00427154 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00427154 about?
NCT00427154 is a clinical study titled "Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes". This trial is conducted in the United States of America (USA). This trial will compare the changes in HbA1c after 26 weeks of inhaled insulin or rosiglitazone treatment, both in combination with metformin and glimepiride.
What is the current status of trial NCT00427154?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 227 participants. The study started on 2007-01-10. Estimated completion is 2008-03-11.
What interventions are being tested in trial NCT00427154?
The interventions under investigation include: metformin (DRUG), rosiglitazone (DRUG), glimepiride (DRUG), inhaled human insulin (DRUG).
Who is sponsoring clinical trial NCT00427154?
This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00427154's enrollment target sits among peer trials
227 1310th of 2000 higher than 691 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04751409 · 227 participants · Phase 2
Evaluating the Impact of Limited Compared With Intense Post-Operative Surveillance on Patient-Reported Outcomes in Patients With Stage II-III Soft Tissue Sarcoma of the Trunk and Extremities
- NCT05742360 · 227 participants
Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype
- NCT05890352 · 227 participants · Phase 2
Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment
- NCT05107908 · 228 participants · NA
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI