Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00425464 · ClinicalTrials.gov registry record · Phase 3
A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Synchrony Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction
A Phase 3 study, sponsored by Abbott Medical Optics.
- Terminated
- Registry status
- Phase 3
- Development phase
- 410
- Enrollment target
NCT00425464: Clinical Trial Phase 3 study, sponsored by Abbott Medical Optics.
NCT00425464 is a Phase 3 study that was terminated before completion, run by Abbott Medical Optics. The registered enrollment target is 410 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00425464, a Phase 3 study, was terminated before completion, sponsored by Abbott Medical Optics.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 410 participants
- Enrollment target
Study Summary
The purpose of the study is to determine if the Synchrony Dual Optic Accommodating Intraocular Lens can be used safely and effectively in post cataract extraction subjects
Interventions
- DEVICE Standard Monofocal Intraocular Lens
- DEVICE Synchrony® Dual Optic Intraocular Lens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 410 participants |
| Start Date | 2005-11 |
| Est. Completion | 2013-04 |
| Phase | Phase 3 |
Why NCT00425464 stopped before completion
NCT00425464 is an interventional study that assigns participants to a tested intervention. The registered 410 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard Monofocal Intraocular Lens is the first listed.
NCT00425464 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00425464 about?
NCT00425464 is a clinical study titled "A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Synchrony Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction". The purpose of the study is to determine if the Synchrony Dual Optic Accommodating Intraocular Lens can be used safely and effectively in post cataract extraction subjects
What is the current status of trial NCT00425464?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 410 participants. The study started on 2005-11. Estimated completion is 2013-04.
What interventions are being tested in trial NCT00425464?
The interventions under investigation include: Standard Monofocal Intraocular Lens (DEVICE), Synchrony® Dual Optic Intraocular Lens (DEVICE).
Who is sponsoring clinical trial NCT00425464?
This trial is sponsored by Abbott Medical Optics, which has 14 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00425464's enrollment target sits among peer trials
410 909th of 2000 higher than 1,090 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02043691 · 410 participants · NA
Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies
- NCT03042975 · 410 participants
Imaging Genetics of Laryngeal Dystonia
- NCT05730036 · 410 participants · Phase 3
A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma
- NCT05751473 · 410 participants · NA
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia