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NCT00420615 · ClinicalTrials.gov registry record · Phase 1
Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies
A Phase 1 study, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 34
- Enrollment target
NCT00420615: Completed Phase 1 study, sponsored by Novartis Pharmaceuticals.
NCT00420615 is a Phase 1 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 34 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00420615, a Phase 1 study, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 34 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the potential inhibitory effects of patupilone on metabolism using midazolam and omeprazole as the respective probe drugs.
Interventions
- DRUG Patupilone and Omeprazole
- DRUG Patupilone + Midalzolam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2006-12 |
| Phase | Phase 1 |
What the finished NCT00420615 record still lists
NCT00420615 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 2 interventions - of which Patupilone and Omeprazole is the first listed.
NCT00420615 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00420615 about?
NCT00420615 is a clinical study titled "Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies". The purpose of this study is to evaluate the potential inhibitory effects of patupilone on metabolism using midazolam and omeprazole as the respective probe drugs.
What is the current status of trial NCT00420615?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2006-12.
What interventions are being tested in trial NCT00420615?
The interventions under investigation include: Patupilone and Omeprazole (DRUG), Patupilone + Midalzolam (DRUG).
Who is sponsoring clinical trial NCT00420615?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00420615's enrollment target sits among peer trials
34 1273rd of 2000 higher than 721 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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