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NCT00417027 · ClinicalTrials.gov registry record · NA
Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
A NA study, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 190
- Enrollment target
NCT00417027: Completed NA study, sponsored by Northwestern University.
NCT00417027 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 190 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00417027, a NA study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 190 participants
- Enrollment target
Study Summary
Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decreased need for manual boluses by the anesthesiologist, and greater patient satisfaction. In this technique, the epidural maintenance dose is administered as a bolus by the infusion pump at regular intervals instead of as a continuous infusion. However, the optimal combination of bolus volume and dosing interval has not been determined. At one end of the spectrum, a small volume and short bolus dose interval will likely behave like a continuous infusion. At the other end of the spectrum, a large volume and long bolus dose interval may lead to an increased incidence of breakthrough pain. The purpose of this randomized, double-blind trial was to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia. We hypothesized that manipulation of the programmed intermittent bolus time interval and volume during the maintenance of epidural labor analgesia influences total drug use, quality of analgesia and patient satisfaction.
Primary Outcome
Total bupivacaine from epidural solution administered for labor analgesia normalized per hour of labor.
Interventions
- PROCEDURE Programmed Intermittent Epidural Bolus (PIEB)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2006-08 |
| Est. Completion | 2009-04 |
| Phase | NA |
What the finished NCT00417027 record still lists
NCT00417027 is an interventional study that assigns participants to a tested intervention. The registered 190 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 1 intervention - of which Programmed Intermittent Epidural Bolus (PIEB) is the first listed.
NCT00417027 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00417027 about?
NCT00417027 is a clinical study titled "Programmed Intermittent Epidural Bolus Time Interval and Injection Volume". Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decreased need for manual boluses by the anesthesiologist, and greater patient satisfaction. In this techn...
What is the current status of trial NCT00417027?
This trial is currently completed. It is a NA study. The enrollment target is 190 participants. The study started on 2006-08. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00417027?
The interventions under investigation include: Programmed Intermittent Epidural Bolus (PIEB) (PROCEDURE).
Who is sponsoring clinical trial NCT00417027?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00417027's enrollment target sits among peer trials
190 574th of 2000 higher than 1,425 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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