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NCT00414999 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers
A Phase 1 study of Diabetic Retinopathy and Macular Degeneration, sponsored by TargeGen.
- Completed
- Registry status
- Phase 1
- Development phase
- 44
- Enrollment target
- 1
- Study location
NCT00414999 is a Phase 1 study of Diabetic Retinopathy and Macular Degeneration that has completed, run by TargeGen. The registered enrollment target is 44 participants, below the 1,676-participant average among 57 other Diabetic Retinopathy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00414999, a Phase 1 study of Diabetic Retinopathy and Macular Degeneration, has completed, sponsored by TargeGen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 44 participants
- Enrollment target
- 1
- Study location
Study Summary
The formation of new blood vessels (angiogenesis), blood vessel leakage, and inflammation contribute to the progression of the eye disease, age-related macular degeneration (AMD), which is the leading cause of irreversible, severe loss of vision in people 55 years of age and older in the developed world. TG100801 is a new drug that inhibits ocular angiogenesis, vascular leak, and inflammation in laboratory studies, and may have great utility in the treatment of diseases such as AMD. The purpose of this study is to assess the safety, ocular tolerability, and blood pharmacokinetics of TG100801 at escalating doses in healthy volunteers.
Conditions Studied
Interventions
- DRUG TG100801
Study Locations (1)
Kansas
- Quintiles Phase One Services, Inc. - Lenexa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2006-11 |
| Est. Completion | 2007-02 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00414999
The ClinicalTrials.gov registry entry for NCT00414999 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,676-participant average among 57 other Diabetic Retinopathy trials with a reported enrollment target (97% lower). The listed sponsor is TargeGen, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Diabetic Retinopathy appearing as the primary indexed condition, and to 1 intervention - of which TG100801 is the first listed.
NCT00414999 reports 1 study location spanning 1 distinct geographic area - top geographies include Kansas.
Frequently Asked Questions
What is clinical trial NCT00414999 about?
NCT00414999 is a clinical study titled "A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers". The formation of new blood vessels (angiogenesis), blood vessel leakage, and inflammation contribute to the progression of the eye disease, age-related macular degeneration (AMD), which is the leading cause of irreversible, severe loss of vision in people 55 years of age and older in the developed w...
What is the current status of trial NCT00414999?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2006-11. Estimated completion is 2007-02.
What conditions does trial NCT00414999 study?
This clinical trial studies the following conditions: Diabetic Retinopathy, Macular Degeneration.
What interventions are being tested in trial NCT00414999?
The interventions under investigation include: TG100801 (DRUG).
Who is sponsoring clinical trial NCT00414999?
This trial is sponsored by TargeGen, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00414999 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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