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NCT00414726 · ClinicalTrials.gov registry record · Phase 2

Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial

A Phase 2 study, sponsored by Massachusetts General Hospital.

Terminated
Registry status
Phase 2
Development phase
85
Enrollment target

NCT00414726: Clinical Trial Phase 2 study, sponsored by Massachusetts General Hospital.

NCT00414726 is a Phase 2 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 85 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (36% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00414726, a Phase 2 study, was terminated before completion, sponsored by Massachusetts General Hospital.

TERMINATED
Registry status
Phase 2
Development phase
85 participants
Enrollment target

Study Summary

The purpose of this study is to compare the safety and efficacy of treating individuals with acute ischemic stroke with normobaric oxygen therapy (NBO, given within 9 hours of symptom onset), to standard medical treatment.

Primary Outcome

The NIHSS score ranges from 0 (best score) to 42 (worst score).

Interventions

  • DRUG Room Air
  • DRUG NBO (Normobaric Oxygen)

Trial Details

FieldValue
Enrollment Target 85 participants
Start Date 2007-01
Est. Completion 2009-06
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

Why NCT00414726 stopped before completion

NCT00414726 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (36% lower).

The record links to 0 conditions, and to 2 interventions - of which Room Air is the first listed.

NCT00414726 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00414726 about?

NCT00414726 is a clinical study titled "Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial". The purpose of this study is to compare the safety and efficacy of treating individuals with acute ischemic stroke with normobaric oxygen therapy (NBO, given within 9 hours of symptom onset), to standard medical treatment.

What is the current status of trial NCT00414726?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 85 participants. The study started on 2007-01. Estimated completion is 2009-06.

What interventions are being tested in trial NCT00414726?

The interventions under investigation include: Room Air (DRUG), NBO (Normobaric Oxygen) (DRUG).

Who is sponsoring clinical trial NCT00414726?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00414726's enrollment target sits among peer trials

85 820th of 2000 higher than 1,179 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00414726, the US trial registry maintained by the National Library of Medicine. NCT00414726 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.