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NCT00411333 · ClinicalTrials.gov registry record · Early Phase 1

Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy

A Early Phase 1 study, sponsored by National Eye Institute (NEI).

Completed
Registry status
Early Phase 1
Development phase
100
Enrollment target

NCT00411333: Completed Early Phase 1 study, sponsored by National Eye Institute (NEI).

NCT00411333 is a Early Phase 1 study that has completed, run by National Eye Institute (NEI). The registered enrollment target is 100 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00411333, a Early Phase 1 study, has completed, sponsored by National Eye Institute (NEI).

COMPLETED
Registry status
Early Phase 1
Development phase
100 participants
Enrollment target

Study Summary

The retinal vasculature changes dramatically in patients with diabetic retinopathy especially between non-proliferative and proliferative disease. The retinal vasculature can be imaged and quantified using special dyes. This study will test whether the pattern of the retinal vasculature changes in patients with different levels of diabetic retinopathy can be quantified using computerized image analysis. In addition, the study will evaluate whether new drugs to treat diabetic retinopathy will be able to reverse these vascular changes.

Interventions

  • DRUG triamcinolone acetonide (Kenalog)

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2006-07
Est. Completion 2009-07
Phase Early Phase 1
National Eye Institute (NEI)

221 total trials

What the finished NCT00411333 record still lists

NCT00411333 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% higher).

The record links to 0 conditions, and to 1 intervention - of which triamcinolone acetonide (Kenalog) is the first listed.

NCT00411333 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00411333 about?

NCT00411333 is a clinical study titled "Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy". The retinal vasculature changes dramatically in patients with diabetic retinopathy especially between non-proliferative and proliferative disease. The retinal vasculature can be imaged and quantified using special dyes. This study will test whether the pattern of the retinal vasculature changes in p...

What is the current status of trial NCT00411333?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2006-07. Estimated completion is 2009-07.

What interventions are being tested in trial NCT00411333?

The interventions under investigation include: triamcinolone acetonide (Kenalog) (DRUG).

Who is sponsoring clinical trial NCT00411333?

This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00411333's enrollment target sits among peer trials

100 184th of 2000 higher than 1,783 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00411333, the US trial registry maintained by the National Library of Medicine. NCT00411333 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.