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NCT00408421 · ClinicalTrials.gov registry record · Phase 3
Duloxetine Versus Placebo for Osteoarthritis Knee Pain
A Phase 3 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 231
- Enrollment target
NCT00408421: Completed Phase 3 study, sponsored by Eli Lilly and Company.
NCT00408421 is a Phase 3 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 231 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00408421, a Phase 3 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 231 participants
- Enrollment target
Study Summary
The primary purpose of this study is to determine if duloxetine reduces pain severity in patients with osteoarthritis knee pain.
Primary Outcome
This is an ordinal scale assessing the 24-hour average pain with scores from 0 (no pain) to 10 (worst possible pain).
Interventions
- DRUG Duloxetine
- DRUG placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 231 participants |
| Start Date | 2006-11 |
| Est. Completion | 2007-10 |
| Phase | Phase 3 |
What the finished NCT00408421 record still lists
NCT00408421 is an interventional study that assigns participants to a tested intervention. The registered 231 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Duloxetine is the first listed.
NCT00408421 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00408421 about?
NCT00408421 is a clinical study titled "Duloxetine Versus Placebo for Osteoarthritis Knee Pain". The primary purpose of this study is to determine if duloxetine reduces pain severity in patients with osteoarthritis knee pain.
What is the current status of trial NCT00408421?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 231 participants. The study started on 2006-11. Estimated completion is 2007-10.
What interventions are being tested in trial NCT00408421?
The interventions under investigation include: Duloxetine (DRUG), placebo (DRUG).
Who is sponsoring clinical trial NCT00408421?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00408421's enrollment target sits among peer trials
231 1300th of 2000 higher than 697 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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