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COMPLETED Phase 3

A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis

NCT00404612 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with active non-infectious uveitis

Interventions

  • DRUG Placebo
  • DRUG LX211

Study Locations (20)

Texas

  • Texas Retina Associates — Arlington
  • Retina Research Center — Austin
  • Texas Retina Associates — Dallas
  • Vitreoretinal Consultants — Houston
  • Retina & Uveitis Consultants of Texas — San Antonio

Massachusetts

  • Massachusetts Eye and Ear Infirmary — Boston
  • Massachusetts Eye Research and Surgery Institute — Cambridge

Alabama

  • University of Alabama at Birmingham — Birmingham

Arizona

  • Retinal Consultants of Arizona — Phoenix

Illinois

  • University of Illinois - Chicago — Chicago

Indiana

  • Midwest Eye Institute — Indianapolis

Maryland

  • Wilmer Eye Institute — Baltimore

Michigan

  • Associated Retinal Consultants, PC — Grand Rapids

Trial Details

FieldValue
Enrollment Target 218 participants
Start Date 2007-01
Est. Completion 2009-05
Phase Phase 3

Sponsor

Lux Biosciences

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00404612

The ClinicalTrials.gov registry entry for NCT00404612 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 218 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Lux Biosciences, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Uveitis, Posterior appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00404612 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Texas, Massachusetts, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00404612 about?

NCT00404612 is a clinical study titled "A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis". The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with active non-infectious uveitis

What is the current status of trial NCT00404612?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 218 participants. The study started on 2007-01. Estimated completion is 2009-05.

What conditions does trial NCT00404612 study?

This clinical trial studies the following conditions: Uveitis, Posterior, Uveitis, Intermediate, Panuveitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00404612?

The interventions under investigation include: Placebo (DRUG), LX211 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00404612?

This trial is sponsored by Lux Biosciences, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00404612 being conducted?

This trial has 20 study locations across Alabama, Arizona, Illinois, Indiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial