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NCT00402714 · ClinicalTrials.gov registry record · Phase 2

A Trial of Extracorporeal Photopheresis, Pentostatin, and Total Body Irradiation in Patients Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation for the Treatment of Malignancies

A Phase 2 study of Hematologic Malignancies, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
14
Enrollment target
3
Study locations

NCT00402714 is a Phase 2 study of Hematologic Malignancies that has completed, run by Yale University. The registered enrollment target is 14 participants, below the 2,712-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT00402714, a Phase 2 study of Hematologic Malignancies, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
14 participants
Enrollment target
3
Study locations

Study Summary

This is a study to explore the use of a reduced intensity transplant conditioning regimen. A conditioning regimen is the treatment that is given to prepare a body for the new bone marrow that will be received from a donor. Reduced intensity conditioning uses lower doses of chemotherapy than conventional conditioning regimens. The use of lower doses of drugs and radiation cause fewer side effects. Reduced intensity regimens have been offered to older patients or patients at increased risk for transplant-related side effects and have been shown to be safe and effective. Reduced intensity conditioning regimens are now considered for many patients who are undergoing transplant.

Conditions Studied

Hematologic Malignancies

Interventions

  • RADIATION Total Body Irradiation
  • DRUG Pentostatin
  • PROCEDURE extracorporeal photopheresis

Study Locations (3)

Connecticut

  • Yale Comprehensive Cancer Center at Yale University School of Medicine - New Haven

Massachusetts

  • Tufts-New England Medical Center - Boston

Texas

  • Methodist Hospital - Texas Transplant Institute - San Antonio

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2006-07
Est. Completion 2009-08
Phase Phase 2

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT00402714

The ClinicalTrials.gov registry entry for NCT00402714 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,712-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (99% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hematologic Malignancies appearing as the primary indexed condition, and to 3 interventions - of which Total Body Irradiation is the first listed.

NCT00402714 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Connecticut, Massachusetts, Texas.

Frequently Asked Questions

What is clinical trial NCT00402714 about?

NCT00402714 is a clinical study titled "A Trial of Extracorporeal Photopheresis, Pentostatin, and Total Body Irradiation in Patients Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation for the Treatment of Malignancies". This is a study to explore the use of a reduced intensity transplant conditioning regimen. A conditioning regimen is the treatment that is given to prepare a body for the new bone marrow that will be received from a donor. Reduced intensity conditioning uses lower doses of chemotherapy than conventi...

What is the current status of trial NCT00402714?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2006-07. Estimated completion is 2009-08.

What conditions does trial NCT00402714 study?

This clinical trial studies the following conditions: Hematologic Malignancies.

What interventions are being tested in trial NCT00402714?

The interventions under investigation include: Total Body Irradiation (RADIATION), Pentostatin (DRUG), extracorporeal photopheresis (PROCEDURE).

Who is sponsoring clinical trial NCT00402714?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00402714 being conducted?

This trial has 3 study locations across Connecticut, Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.