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NCT00402363 · ClinicalTrials.gov registry record · Phase 3

Evaluation of Efficacy and Safety of Lovaza (Omega-3-Acid Ethyl Esters) in Recurrent, Symptomatic Atrial Fibrillation

A Phase 3 study of Fibrillation, Atrial, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 3
Development phase
663
Enrollment target
20
Study locations

NCT00402363: Completed Phase 3 study of Fibrillation, Atrial, sponsored by GlaxoSmithKline.

NCT00402363 is a Phase 3 study of Fibrillation, Atrial that has completed, run by GlaxoSmithKline. The registered enrollment target is 663 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (14% lower). The trial reports 20 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00402363, a Phase 3 study of Fibrillation, Atrial, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 3
Development phase
663 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate efficacy and safety of Omacor (omega-3-acid ethyl esters) in patients with recurrent, symptomatic atrial fibrillation.

Primary Outcome

A documented episode of symptomatic AF /Flutter was defined as AF/Flutter documented by an electrocardiogram (ECG) or transtelephonic monitoring (TTM) tracing associated with symptoms consistent with AF. Atrial flutter, a closely related rhythm disorder, was distinguished from AF by the presence of distinctive flutter p-waves at regluar intervals. The occurrence of symptomatic atrial flutter was treated as an occurrence of symptomatic AF for this outcome measure. "Censored" in the table below re

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG omega-3-acid ethyl esters

Study Locations (20)

California

  • GSK Investigational Site - Alamada
  • GSK Investigational Site - Bakersfield
  • GSK Investigational Site - Bakersfield
  • GSK Investigational Site - Beverly Hills
  • GSK Investigational Site - Carmichael
  • GSK Investigational Site - Fair Oaks
  • GSK Investigational Site - Fountain Valley
  • GSK Investigational Site - Loma Linda
  • GSK Investigational Site - Los Angeles

Arizona

  • GSK Investigational Site - Cottonwood
  • GSK Investigational Site - Mesa
  • GSK Investigational Site - Phoenix
  • GSK Investigational Site - Phoenix
  • GSK Investigational Site - Phoenix
  • GSK Investigational Site - Tucson

Alabama

  • GSK Investigational Site - Birmingham
  • GSK Investigational Site - Huntsville

Arkansas

  • GSK Investigational Site - Fort Smith
  • GSK Investigational Site - Hot Springs

Alaska

  • GSK Investigational Site - Anchorage

Trial Details

FieldValue
Enrollment Target 663 participants
Start Date 2006-11
Est. Completion 2010-01
Phase Phase 3
GlaxoSmithKline

1,345 total trials

What the finished NCT00402363 record still lists

NCT00402363 is an interventional study that assigns participants to a tested intervention. The registered 663 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (14% lower).

The record links to 1 condition, with Fibrillation, Atrial appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00402363 names 20 study sites across 5 states, led by California, Arizona, Alabama.

Frequently Asked Questions

What is clinical trial NCT00402363 about?

NCT00402363 is a clinical study titled "Evaluation of Efficacy and Safety of Lovaza (Omega-3-Acid Ethyl Esters) in Recurrent, Symptomatic Atrial Fibrillation". The purpose of this study is to evaluate efficacy and safety of Omacor (omega-3-acid ethyl esters) in patients with recurrent, symptomatic atrial fibrillation.

What is the current status of trial NCT00402363?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 663 participants. The study started on 2006-11. Estimated completion is 2010-01.

What conditions does trial NCT00402363 study?

This clinical trial studies the following conditions: Fibrillation, Atrial.

What interventions are being tested in trial NCT00402363?

The interventions under investigation include: Placebo (DRUG), omega-3-acid ethyl esters (DRUG).

Who is sponsoring clinical trial NCT00402363?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00402363 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT00402363's enrollment target sits among peer trials

663 553rd of 2000 higher than 1,447 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00402363, the US trial registry maintained by the National Library of Medicine. NCT00402363 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.