Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00395421 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate Drug-drug Interaction Between Valopicitabine and Ribavirin
A Phase 2 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 2
- Development phase
- 114
- Enrollment target
NCT00395421: Completed Phase 2 study, sponsored by Merck Sharp & Dohme.
NCT00395421 is a Phase 2 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 114 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00395421, a Phase 2 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 114 participants
- Enrollment target
Study Summary
This study is being conducted to see if the investigational medication, valopicitabine, is safe to use in combination with ribavirin, a drug approved by the FDA for treating hepatitis C infection.
Interventions
- DRUG NM283 plus Peg-IFNα-2a
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2006-10 |
| Est. Completion | 2008-08 |
| Phase | Phase 2 |
What the finished NCT00395421 record still lists
NCT00395421 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower).
The record links to 0 conditions, and to 1 intervention - of which NM283 plus Peg-IFNα-2a is the first listed.
NCT00395421 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00395421 about?
NCT00395421 is a clinical study titled "Study to Evaluate Drug-drug Interaction Between Valopicitabine and Ribavirin". This study is being conducted to see if the investigational medication, valopicitabine, is safe to use in combination with ribavirin, a drug approved by the FDA for treating hepatitis C infection.
What is the current status of trial NCT00395421?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 114 participants. The study started on 2006-10. Estimated completion is 2008-08.
What interventions are being tested in trial NCT00395421?
The interventions under investigation include: NM283 plus Peg-IFNα-2a (DRUG).
Who is sponsoring clinical trial NCT00395421?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00395421's enrollment target sits among peer trials
114 627th of 2000 higher than 1,370 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04522791 · 114 participants · Phase 2
Breathing, Relaxation, Attention Training, & Health in Older Adults (BREATHE)
- NCT04875052 · 114 participants · NA
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
- NCT05100342 · 114 participants
Prospective Validation of a Points Score System Predicting 30-day Survival
- NCT05224089 · 114 participants · Phase 4
Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia