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NCT00376896 · ClinicalTrials.gov registry record · Phase 1

Study On The Effect Of GW876008 On Cerebral Blood Flow In Irritable Bowel Syndrome (IBS) Patients And Healthy Volunteers

A Phase 1 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT00376896: Completed Phase 1 study, sponsored by GlaxoSmithKline.

NCT00376896 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00376896, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

This is a three-period crossover study to compare GW876008 and placebo to see if GW876008 will normalise blood flow responses after different emotional stimuli.

Interventions

  • OTHER Placebo
  • DRUG GW876008 200mcg
  • DRUG GW876008 20mcg

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2006-11
Est. Completion 2008-10
Phase Phase 1
GlaxoSmithKline

1,345 total trials

What the finished NCT00376896 record still lists

NCT00376896 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00376896 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00376896 about?

NCT00376896 is a clinical study titled "Study On The Effect Of GW876008 On Cerebral Blood Flow In Irritable Bowel Syndrome (IBS) Patients And Healthy Volunteers". This is a three-period crossover study to compare GW876008 and placebo to see if GW876008 will normalise blood flow responses after different emotional stimuli.

What is the current status of trial NCT00376896?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2006-11. Estimated completion is 2008-10.

What interventions are being tested in trial NCT00376896?

The interventions under investigation include: Placebo (OTHER), GW876008 200mcg (DRUG), GW876008 20mcg (DRUG).

Who is sponsoring clinical trial NCT00376896?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00376896's enrollment target sits among peer trials

25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00376896, the US trial registry maintained by the National Library of Medicine. NCT00376896 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.