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NCT00362570 · ClinicalTrials.gov registry record · Phase 2

Temozolomide in Patients With Newly Diagnosed Anaplastic Oligodendroglioma and Mixed Oligoastrocytoma

A Phase 2 study, sponsored by Ohio State University Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
1
Enrollment target

NCT00362570: Completed Phase 2 study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT00362570 is a Phase 2 study that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 1 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00362570, a Phase 2 study, has completed, sponsored by Ohio State University Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

Rationale: Standard therapy for anaplastic oligodendrogliomas and mixed oligoastrocytomas includes radiation and chemotherapy. However, due to the potential long-term central nervous system toxicity from radiation, researchers speculate that it may be better to reserve radiation therapy for progressive disease. In addition, some patients with anaplastic oligodendroglioma and mixed oligoastrocytoma have unusually chemosensitive tumors. Previous research indicates that brain tumor patients with a deletion of the 1p chromosome have a higher response to the chemotherapy drug temozolomide.

Interventions

  • DRUG Temozolomide

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2005-05
Est. Completion 2011-03
Phase Phase 2

What the finished NCT00362570 record still lists

NCT00362570 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Temozolomide is the first listed.

NCT00362570 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00362570 about?

NCT00362570 is a clinical study titled "Temozolomide in Patients With Newly Diagnosed Anaplastic Oligodendroglioma and Mixed Oligoastrocytoma". Rationale: Standard therapy for anaplastic oligodendrogliomas and mixed oligoastrocytomas includes radiation and chemotherapy. However, due to the potential long-term central nervous system toxicity from radiation, researchers speculate that it may be better to reserve radiation therapy for progres...

What is the current status of trial NCT00362570?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2005-05. Estimated completion is 2011-03.

What interventions are being tested in trial NCT00362570?

The interventions under investigation include: Temozolomide (DRUG).

Who is sponsoring clinical trial NCT00362570?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00362570's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00362570, the US trial registry maintained by the National Library of Medicine. NCT00362570 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.