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NCT00359073 · ClinicalTrials.gov registry record · NA
Effect of Montelukast on Experimentally-Induced RV16 Infection in Asthma
A NA study, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT00359073 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 25 participants.
The verdict
NCT00359073, a NA study, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
People with asthma may have asthma worsening when they have an upper respiratory infection due to a virus or a common cold. Leukotrienes are increased in nasal secretions from children with Respiratory Syncytial Virus (RSV) and lung washings during times of acute lung inflammation. Experimental virus exposure in adults is also associated with increases in nasal leukotrienes. The degree to which leukotrienes play a role in asthma worsening is unknown.There is information linking leukotrienes to viral infections, allergic inflammation, and asthma exacerbation.This information supports the hypothesis that virus-induced leukotrienes contribute to the severity of respiratory infections and in susceptible individuals, lead to lower airway obstruction and exacerbations of asthma. We propose to use montelukast in an experimental viral challenge model to explore this hypothesis.
Interventions
- DRUG placebo
- DRUG montelukast
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2006-10 |
| Est. Completion | 2009-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00359073
The ClinicalTrials.gov registry entry for NCT00359073 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT00359073 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00359073 about?
NCT00359073 is a clinical study titled "Effect of Montelukast on Experimentally-Induced RV16 Infection in Asthma". People with asthma may have asthma worsening when they have an upper respiratory infection due to a virus or a common cold. Leukotrienes are increased in nasal secretions from children with Respiratory Syncytial Virus (RSV) and lung washings during times of acute lung inflammation. Experimental viru...
What is the current status of trial NCT00359073?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2006-10. Estimated completion is 2009-01.
What interventions are being tested in trial NCT00359073?
The interventions under investigation include: placebo (DRUG), montelukast (DRUG).
Who is sponsoring clinical trial NCT00359073?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
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