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NCT00357448 · ClinicalTrials.gov registry record · Phase 1
Denileukin Diftitox Used in Treating Patients With Advanced Refractory Ovarian Cancer, Primary Peritoneal Carcinoma, or Epithelial Fallopian Tube Cancer
A Phase 1 study, sponsored by University of Washington.
- Completed
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT00357448: Completed Phase 1 study, sponsored by University of Washington.
NCT00357448 is a Phase 1 study that has completed, run by University of Washington. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00357448, a Phase 1 study, has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
RATIONALE: Biological therapies, such as denileukin difitox, may stimulate the immune system in different ways and may prevent tumor cells from growing. PURPOSE: This phase I trial is studying the side effects and best dose of denileukin diftitox in treating patients with advanced refractory ovarian cancer, primary peritoneal carcinoma, or epithelial fallopian tube cancer.
Interventions
- OTHER laboratory biomarker analysis
- OTHER flow cytometry
- OTHER enzyme-linked immunosorbent assay
- BIOLOGICAL denileukin diftitox
- PROCEDURE intraperitoneal administration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2005-04 |
| Phase | Phase 1 |
What the finished NCT00357448 record still lists
NCT00357448 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.
NCT00357448 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00357448 about?
NCT00357448 is a clinical study titled "Denileukin Diftitox Used in Treating Patients With Advanced Refractory Ovarian Cancer, Primary Peritoneal Carcinoma, or Epithelial Fallopian Tube Cancer". RATIONALE: Biological therapies, such as denileukin difitox, may stimulate the immune system in different ways and may prevent tumor cells from growing. PURPOSE: This phase I trial is studying the side effects and best dose of denileukin diftitox in treating patients with advanced refractory ovarian...
What is the current status of trial NCT00357448?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2005-04.
What interventions are being tested in trial NCT00357448?
The interventions under investigation include: laboratory biomarker analysis (OTHER), flow cytometry (OTHER), enzyme-linked immunosorbent assay (OTHER), denileukin diftitox (BIOLOGICAL), intraperitoneal administration (PROCEDURE).
Who is sponsoring clinical trial NCT00357448?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00357448's enrollment target sits among peer trials
11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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