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NCT00356187 · ClinicalTrials.gov registry record · Phase 2
Beta Blockade in Critical Injury
A Phase 2 study, sponsored by Denver Health and Hospital Authority.
- Terminated
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT00356187: Clinical Trial Phase 2 study, sponsored by Denver Health and Hospital Authority.
NCT00356187 is a Phase 2 study that was terminated before completion, run by Denver Health and Hospital Authority. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00356187, a Phase 2 study, was terminated before completion, sponsored by Denver Health and Hospital Authority.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
Critically injured patients endure a period of hypermetabolism/catabolism after being resuscitated. The metabolic cost of this may be measured in loss of lean body mass, poor wound healing, susceptibility to infection and long hospital stays. While there have been some data to suggest that hypermetabolism can be ameliorated in burn patients by beta blockade, to our knowledge, a prospective trial in trauma patients has not yet been done. Our hypothesis is that nonselective beta blockade will reduce catabolism, improve glucose control, blunt loss of lean body mass, decrease infections and improve outcome in a cohort of critically injured patients.
Interventions
- DRUG Propranolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2006-02-15 |
| Est. Completion | 2009-01-31 |
| Phase | Phase 2 |
Why NCT00356187 stopped before completion
NCT00356187 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 1 intervention - of which Propranolol is the first listed.
NCT00356187 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00356187 about?
NCT00356187 is a clinical study titled "Beta Blockade in Critical Injury". Critically injured patients endure a period of hypermetabolism/catabolism after being resuscitated. The metabolic cost of this may be measured in loss of lean body mass, poor wound healing, susceptibility to infection and long hospital stays. While there have been some data to suggest that hypermeta...
What is the current status of trial NCT00356187?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2006-02-15. Estimated completion is 2009-01-31.
What interventions are being tested in trial NCT00356187?
The interventions under investigation include: Propranolol (DRUG).
Who is sponsoring clinical trial NCT00356187?
This trial is sponsored by Denver Health and Hospital Authority, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00356187's enrollment target sits among peer trials
15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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