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NCT00354393 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma
A Phase 2 study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT00354393 is a Phase 2 study that has completed, run by The Cleveland Clinic. The registered enrollment target is 9 participants.
The verdict
NCT00354393, a Phase 2 study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as methotrexate, vinorelbine, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Radiation therapy uses high-energy x-rays to kill tumor cells. Cisplatin may also make tumor cells more sensitive to radiation therapy. Giving chemotherapy and radiation therapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well giving combination chemotherapy with or without surgery and chemoradiotherapy works in treating patients with malignant pleural mesothelioma.
Interventions
- DRUG Cisplatin
- DRUG Methotrexate
- PROCEDURE Adjuvant therapy
- PROCEDURE Conventional surgery
- DRUG Vinorelbine ditartrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2002-08 |
| Est. Completion | 2009-06 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00354393
The ClinicalTrials.gov registry entry for NCT00354393 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Cisplatin is the first listed.
NCT00354393 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00354393 about?
NCT00354393 is a clinical study titled "Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma". RATIONALE: Drugs used in chemotherapy, such as methotrexate, vinorelbine, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of nor...
What is the current status of trial NCT00354393?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2002-08. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00354393?
The interventions under investigation include: Cisplatin (DRUG), Methotrexate (DRUG), Adjuvant therapy (PROCEDURE), Conventional surgery (PROCEDURE), Vinorelbine ditartrate (DRUG).
Who is sponsoring clinical trial NCT00354393?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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