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NCT00352482 · ClinicalTrials.gov registry record · Phase 2

Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension

A Phase 2 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

Completed
Registry status
Phase 2
Development phase
20
Enrollment target

NCT00352482: Completed Phase 2 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

NCT00352482 is a Phase 2 study that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00352482, a Phase 2 study, has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target

Study Summary

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. Currently, no medications can reverse the damage to the lungs caused by IPF, but individuals are encouraged to engage in moderate exercise to strengthen lung function. This study will evaluate the effectiveness of sildenafil at improving exercise tolerance and breathing difficulties in individuals with IPF.

Interventions

  • DRUG Sildenafil (50 mg)

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2004-11
Est. Completion 2007-07
Phase Phase 2

What the finished NCT00352482 record still lists

NCT00352482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 1 intervention - of which Sildenafil (50 mg) is the first listed.

NCT00352482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00352482 about?

NCT00352482 is a clinical study titled "Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension". Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. Currently, no medications can reverse the damage to the lungs caused by IPF, but individuals are encouraged to engage in moderate exercise to strengthen lung function. This study will evalu...

What is the current status of trial NCT00352482?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2004-11. Estimated completion is 2007-07.

What interventions are being tested in trial NCT00352482?

The interventions under investigation include: Sildenafil (50 mg) (DRUG).

Who is sponsoring clinical trial NCT00352482?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00352482's enrollment target sits among peer trials

20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00352482, the US trial registry maintained by the National Library of Medicine. NCT00352482 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.