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NCT00347776 · ClinicalTrials.gov registry record · Phase 4
Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia
A Phase 4 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 4
- Development phase
- 1,452
- Enrollment target
NCT00347776: Completed Phase 4 study, sponsored by Johns Hopkins University.
NCT00347776 is a Phase 4 study that has completed, run by Johns Hopkins University. The registered enrollment target is 1,452 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00347776, a Phase 4 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 1,452 participants
- Enrollment target
Study Summary
Trachoma, an ocular infection caused by C. trachomatis, is the second leading cause of blindness worldwide.Years of repeated infection with C. trachomatis cause the eyelid to scar and contract and ultimately to rotate inward such that eyelashes rub against the eyeball and abrade the cornea (trichiasis). The World Health Organization (WHO) has endorsed a multi-faceted strategy to combat trachoma, which includes surgery to correct trichiasis. Despite this encouraging news, under the best of circumstances the recurrence rate of trichiasis following surgery is disappointingly high. The objective of our project is to conduct a randomized, controlled clinical trial of post-surgical antibiotic treatment, comparing oral azithromycin to topical tetracycline, for trichiasis surgical patients in Ethiopia with the goal of determining the impact of treatment on rates of trichiasis recurrence at one and two years.
Interventions
- DRUG azithromycin
- DRUG topical tetracycline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,452 participants |
| Start Date | 2001-08 |
| Est. Completion | 2006-12 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00347776
The ClinicalTrials.gov registry entry for NCT00347776 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 1,452 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which azithromycin is the first listed.
NCT00347776 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00347776 about?
NCT00347776 is a clinical study titled "Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia". Trachoma, an ocular infection caused by C. trachomatis, is the second leading cause of blindness worldwide.Years of repeated infection with C. trachomatis cause the eyelid to scar and contract and ultimately to rotate inward such that eyelashes rub against the eyeball and abrade the cornea (trichias...
What is the current status of trial NCT00347776?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 1,452 participants. The study started on 2001-08. Estimated completion is 2006-12.
What interventions are being tested in trial NCT00347776?
The interventions under investigation include: azithromycin (DRUG), topical tetracycline (DRUG).
Who is sponsoring clinical trial NCT00347776?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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