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NCT00342407 · ClinicalTrials.gov registry record
The Incidence of Breast and Other Cancers Among Female Flight Attendants
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 6,093
- Enrollment target
NCT00342407: Completed study, sponsored by National Cancer Institute (NCI).
NCT00342407 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 6,093 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00342407 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 6,093 participants
- Enrollment target
Study Summary
Flight attendants may be at an increased risk of breast and other cancers due to work-place exposures including cosmic radiation and circadian rhythm disruption form traveling across multiple time zones. This cancer incidence study will determine whether female flight attendants are at increased risk of breast and other cancers and whether the risk is dose-related. The study will include a cohort of approximately 10,000 women who were employed as flight attendants for one or more years. Breast cancer cases will be identified from telephone interviews of living subjects and next-of-kin of deceased subjects, as well as from death certificates. The interview will also provide information about non-occupational risk factors for breast cancer such as parity. Both internal and external comparisons will be made. The primary analysis will evaluate the risk associated with occupational exposure within the cohort, controlling for non-occupational risk factors by stratification or modeling. The secondary analysis will compare the incidence of breast cancer in the cohort to that in the general population, with adjustment for factors such as lower parity which might increase breast cancer risk in the cohort independent of occupational exposure to cosmic radiation and circadian rhythm disruption. The risk of other ionizing radiation-related cancers, such as leukemia, lung cancer, and thyroid cancer, among flight attendants will also be evaluated. The results of the study will apply to female flight crew and frequent fliers.
Primary Outcome
survival
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6,093 participants |
| Start Date | 2001-11-06 |
| Est. Completion | 2020-04-09 |
What the finished NCT00342407 record still lists
NCT00342407 is an observational study that tracks outcomes without assigning an intervention. Its 6,093 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00342407 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00342407 about?
NCT00342407 is a clinical study titled "The Incidence of Breast and Other Cancers Among Female Flight Attendants". Flight attendants may be at an increased risk of breast and other cancers due to work-place exposures including cosmic radiation and circadian rhythm disruption form traveling across multiple time zones. This cancer incidence study will determine whether female flight attendants are at increased ris...
What is the current status of trial NCT00342407?
This trial is currently completed. The enrollment target is 6,093 participants. The study started on 2001-11-06. Estimated completion is 2020-04-09.
Who is sponsoring clinical trial NCT00342407?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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