Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00341263 · ClinicalTrials.gov registry record

Maternal and Umbilical Cord Hormone Concentrations in Twin and Singleton Pregnancies

A clinical trial, sponsored by National Cancer Institute (NCI).

Completed
Registry status
111
Enrollment target

NCT00341263: Completed study, sponsored by National Cancer Institute (NCI).

NCT00341263 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 111 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT00341263 has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
111 participants
Enrollment target

Study Summary

This study will examine levels of hormones, such as estrogen and testosterone, in maternal and umbilical cord blood to compare hormones between mothers who are having twins and mothers who are having one baby. It will investigate whether hormone levels in twin versus singleton pregnancies influence the babies' risk of developing breast, prostate, and testicular cancers later in life. Pregnant women 18 years of age and older who do not have preeclampsia, chronic hypertension, pre-pregnancy or gestational diabetes, thyroid disease, or other major pregnancy complications are eligible for this study. Participants will be recruited from the obstetrics and gynecology practice at the Dartmouth Hitchcock Medical Center in Lebanon, New Hampshire. Participants will have a blood sample drawn from their arm during their third trimester prenatal visit and again when they are admitted to the hospital for delivery. After the baby is born, a blood sample will be collected from the cut umbilical cord. Information about the pregnancy and delivery will be collected from the mother's medical chart, and information about the baby's size will be obtained from the baby's medical chart.

Primary Outcome

Analysis of maternal and cord blood hormone concentrations inmonochorionic twin, dichorionic twin and singleton pregnancies of similar gestational age--especially with respect to cancer risk.

Trial Details

FieldValue
Enrollment Target 111 participants
Start Date 2003-11-21
Est. Completion 2020-02-19
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00341263 record still lists

NCT00341263 is an observational study that tracks outcomes without assigning an intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT00341263 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00341263 about?

NCT00341263 is a clinical study titled "Maternal and Umbilical Cord Hormone Concentrations in Twin and Singleton Pregnancies". This study will examine levels of hormones, such as estrogen and testosterone, in maternal and umbilical cord blood to compare hormones between mothers who are having twins and mothers who are having one baby. It will investigate whether hormone levels in twin versus singleton pregnancies influence ...

What is the current status of trial NCT00341263?

This trial is currently completed. The enrollment target is 111 participants. The study started on 2003-11-21. Estimated completion is 2020-02-19.

Who is sponsoring clinical trial NCT00341263?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03875716 · 111 participants · NA

    Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

  • NCT04693468 · 111 participants · Phase 1

    Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

  • NCT05263050 · 111 participants · Phase 2

    Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

  • NCT05600842 · 111 participants

    De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT00341263, the US trial registry maintained by the National Library of Medicine. NCT00341263 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.