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NCT00331526 · ClinicalTrials.gov registry record · Phase 2

Cellular Adoptive Immunotherapy in Treating Patients With Glioblastoma Multiforme

A Phase 2 study, sponsored by Hoag Memorial Hospital Presbyterian.

Completed
Registry status
Phase 2
Development phase
83
Enrollment target

NCT00331526: Completed Phase 2 study, sponsored by Hoag Memorial Hospital Presbyterian.

NCT00331526 is a Phase 2 study that has completed, run by Hoag Memorial Hospital Presbyterian. The registered enrollment target is 83 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00331526, a Phase 2 study, has completed, sponsored by Hoag Memorial Hospital Presbyterian.

COMPLETED
Registry status
Phase 2
Development phase
83 participants
Enrollment target

Study Summary

RATIONALE: Biological therapies, such as cellular adoptive immunotherapy, may stimulate the immune system in different ways and stop tumor cells from growing. Aldesleukin may stimulate the white blood cells, including lymphokine-activated killer cells, to kill tumor cells. Giving cellular adoptive immunotherapy during or after surgery may kill more tumor cells. PURPOSE: This phase II trial is studying how well cellular adoptive immunotherapy works in treating patients with glioblastoma multiforme.

Interventions

  • PROCEDURE conventional surgery
  • BIOLOGICAL therapeutic autologous lymphocytes
  • BIOLOGICAL aldesleukin
  • PROCEDURE adjuvant therapy

Trial Details

FieldValue
Enrollment Target 83 participants
Start Date 1999-02
Est. Completion 2012-04
Phase Phase 2

What the finished NCT00331526 record still lists

NCT00331526 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 83 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (38% lower).

The record links to 0 conditions, and to 4 interventions - of which conventional surgery is the first listed.

NCT00331526 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00331526 about?

NCT00331526 is a clinical study titled "Cellular Adoptive Immunotherapy in Treating Patients With Glioblastoma Multiforme". RATIONALE: Biological therapies, such as cellular adoptive immunotherapy, may stimulate the immune system in different ways and stop tumor cells from growing. Aldesleukin may stimulate the white blood cells, including lymphokine-activated killer cells, to kill tumor cells. Giving cellular adoptive i...

What is the current status of trial NCT00331526?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 83 participants. The study started on 1999-02. Estimated completion is 2012-04.

What interventions are being tested in trial NCT00331526?

The interventions under investigation include: conventional surgery (PROCEDURE), therapeutic autologous lymphocytes (BIOLOGICAL), aldesleukin (BIOLOGICAL), adjuvant therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00331526?

This trial is sponsored by Hoag Memorial Hospital Presbyterian, which has 20 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00331526's enrollment target sits among peer trials

83 828th of 2000 higher than 1,171 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00331526, the US trial registry maintained by the National Library of Medicine. NCT00331526 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.