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NCT00330967 · ClinicalTrials.gov registry record
Mechanisms of Insulin Resistance in Humans
A clinical trial, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- 25
- Enrollment target
NCT00330967: Completed study, sponsored by US Department of Veterans Affairs.
NCT00330967 is a clinical trial that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 25 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00330967 has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- 25 participants
- Enrollment target
Study Summary
The Objectives of the study are to: (1)compare the inflammatory response and insulin resistance in skeletal muscles during a systemic infusion of lipid with that during a local infusion of lipid into the femoral artery. which would cause minimal or no systemic hyperlipidemia but local plasma free fatty acid (FFA) concentrations similar to those during the systemic lipid infusion, and (2) determine the inflammatory response and insulin resistance in skeletal muscle during an infusion of lipid into the femoral artery as described above after NF-KB inhibition by high dose salicylate treatment in humans.
Primary Outcome
IRS-1 expression in response to femoral lipid infusion in skeletal muscle. Relative protein expression was calculated by densitometry analysis of Western blot bands, normalized to a housekeeping protein, GAPDH, in control and treated groups.
Interventions
- DRUG 20% Intralipid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2006-04 |
| Est. Completion | 2014-08 |
What the finished NCT00330967 record still lists
NCT00330967 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which 20% Intralipid is the first listed.
NCT00330967 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00330967 about?
NCT00330967 is a clinical study titled "Mechanisms of Insulin Resistance in Humans". The Objectives of the study are to: (1)compare the inflammatory response and insulin resistance in skeletal muscles during a systemic infusion of lipid with that during a local infusion of lipid into the femoral artery. which would cause minimal or no systemic hyperlipidemia but local plasma free fa...
What is the current status of trial NCT00330967?
This trial is currently completed. The enrollment target is 25 participants. The study started on 2006-04. Estimated completion is 2014-08.
What interventions are being tested in trial NCT00330967?
The interventions under investigation include: 20% Intralipid (DRUG).
Who is sponsoring clinical trial NCT00330967?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
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